Angiotensin III (human, mouse)

Discontinued Product

Unfortunately Angiotensin III (human, mouse) (Cat. No. 1564) has been withdrawn from sale for commercial reasons.
Cat.No. 1564 - Angiotensin III (human, mouse) | Arg-Val-Tyr-Ile-His-Pro-Phe | CAS No. 13602-53-4
Description: Vasoconstrictor peptide

Biological Activity

Endogenous vasoconstrictor peptide, formed from the conversion of angiotensin II in vivo. Acts at both AT1 and AT2 receptors and increases vasopressin (anti-diuretic hormone) release and blood pressure.

Technical Data

M. Wt 931.09
Formula C46H66N12O9
Sequence RVYIHPF
Storage Desiccate at -20°C
CAS Number 13602-53-4
Smiles [H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 931.09. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.07 mL 5.37 mL 10.74 mL
5 mM 0.21 mL 1.07 mL 2.15 mL
10 mM 0.11 mL 0.54 mL 1.07 mL
50 mM 0.02 mL 0.11 mL 0.21 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet


References are publications that support the products' biological activity.

Devynck et al (1977) Specific receptors for des-Asp1-angiotensin II ("angiotensin III") in rat adrenals. Proc.Natl.Acad.Sci.U.S.A. 74 4029 PMID: 198814

Luoh and Chan (1998) Participation of AT1 and AT2 receptor subtypes in the tonic inhibitory modulation of baroreceptor reflex response by endogenous angiotensins at the nucleus tractus solitarii in the rat. Brain Res. 782 73 PMID: 9519251

Reaux et al (2001) Angiotensin III: a central regulator of vasopressin release and blood pressure. Trends Endocrinol.Metab. 12 157 PMID: 11295571

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Citations for Angiotensin III (human, mouse)

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