Amyloid β-Peptide (1-37) (human)

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Cat.No. 7031 - Amyloid beta-Peptide (1-37) (human) | Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly | CAS No. 186359-67-1
Description: Amyloid β-protein fragment
Datasheet
Citations
Reviews
Literature (2)

Biological Activity

Human amyloid β-protein fragment cleaved from amyloid precursor protein (APP). Minor Aβ fragment identified in brains of APP23 mice and human Alzheimer's disease patients.

Technical Data

M. Wt 4074.53
Formula C182H274N50O55S
Sequence DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVG
Storage Store at -20°C
CAS Number 186359-67-1
InChI Key LKNGNRVBKQEJPA-IUMSEVKGSA-N
Smiles [H]N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)NCC(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 1 mg/ml in DMSO

References

References are publications that support the biological activity of the product.

Schieb et al (2011) Beta-amyloid peptide variants in brains and cerebrospinal fluid from amyloid precursor protein (APP) transgenic mice: comparison with human Alzheimer amyloid. J.Biol.Chem. 286 33747 PMID: 21795681


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Keywords: Amyloid beta-Peptide (1-37) (human), Amyloid beta-Peptide (1-37) (human) supplier, amyloid, beta, peptide, 1-37, alzheimers, disease, APP, precusor, protein, Amyloid, Beta, Peptides, 7031, Tocris Bioscience

Citations for Amyloid β-Peptide (1-37) (human)

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