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Discontinued ProductAmbuic Acid (Cat. No. 6547) has been withdrawn from sale for commercial reasons.
Quorum sensing inhibitor. Inhibits auto-inducing peptide (AIP) signal biosynthesis in MRSA (IC50 = 2.5 μM). Reduces MRSA-induced abcess formation in rats. Exhibits activity against pathogenic Gram-positive bacteria but not commensal bacteria.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Todd et al (2017) Signal biosynthesis inhibition with ambuic acid as a strategy to target antibiotic-resistant infections. Antimicrob.Agents Chemother. 61 e00263-17 PMID: 28607020
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Keywords: Ambuic Acid, Ambuic Acid supplier, quorum, sensing, inhibitors, inhibits, antibacterial, auto-inducing, peptide, AIP, signal, biosynthesis, MRSA, methicillin, meticillin, resistant, Staphylococcus, aureus, Antibiotics, 6547, Tocris Bioscience
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