Amphibian bombesin-like peptide. Stimulates gastric acid secretion, intestinal contraction, rat uterine contraction and hypertension in vivo in the dog. Also modulates thermoregulation following central administration in vivo.
(Modifications: X = Glp, Met-14 = C-terminal amide)
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 1 mg/ml in water|
Preparing Stock Solutions
The following data is based on the product molecular weight 1535.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||0.65 mL||3.26 mL||6.51 mL|
|5 mM||0.13 mL||0.65 mL||1.3 mL|
|10 mM||0.07 mL||0.33 mL||0.65 mL|
|50 mM||0.01 mL||0.07 mL||0.13 mL|
References are publications that support the products' biological activity.
Anastasi (1971) Alytesin and bombesin, two peptide analogs from amphibian skin. Naunyn Schmiedebergs Arch.Pharmacol. 269 135 PMID: 4254272
Broccardo et al (1975) Relative potency of bombesin-like peptides. Br.J.Pharmacol. 55 221 PMID: 1201380
Rivier and Brown (1978) Bombesin, bombesin analogues, and related peptides: effects on thermoregulation. Biochemistry 17 1766 PMID: 656396
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Keywords: Alytesin, supplier, Amphibian, bombesin-like, peptide, GRP-Preferring, Receptors, BB1, BB2, BB3, Gastrin-Releasing, Peptide-Preferring, NMB-Preferring, Neuromedin, B-Preferring, Bombesin, Bombesin, Receptors, Bombesin, Receptors, Tocris Bioscience
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
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Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.