Amphibian bombesin-like peptide. Stimulates gastric acid secretion, intestinal contraction, rat uterine contraction and hypertension in vivo in the dog. Also modulates thermoregulation following central administration in vivo.
(Modifications: X = Glp, Met-14 = C-terminal amide)
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 1 mg/ml in water|
References are publications that support the biological activity of the product.
Anastasi (1971) Alytesin and bombesin, two peptide analogs from amphibian skin. Naunyn Schmiedebergs Arch.Pharmacol. 269 135 PMID: 4254272
Broccardo et al (1975) Relative potency of bombesin-like peptides. Br.J.Pharmacol. 55 221 PMID: 1201380
Rivier and Brown (1978) Bombesin, bombesin analogues, and related peptides: effects on thermoregulation. Biochemistry 17 1766 PMID: 656396
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Keywords: Alytesin, Alytesin supplier, Amphibian, bombesin-like, peptide, GRP-Preferring, Receptors, BB1, BB2, BB3, Gastrin-Releasing, Peptide-Preferring, NMB-Preferring, Neuromedin, B-Preferring, Bombesin, 1893, Tocris Bioscience
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Literature in this Area
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Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.