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[Ac-Tyr1,D-Phe2]GRF 1-29, amide (human)

Cat. No. 1172 Submit a Review Datasheet / COA / SDS

Discontinued Product

[Ac-Tyr1,D-Phe2]GRF 1-29, amide (human) (Cat. No. 1172) has been withdrawn from sale for commercial reasons.
Description: VIP receptor antagonist
Datasheet
Citations
Reviews
Literature (2)
Biological Activity Technical Data Datasheets References

Biological Activity

VIP receptor antagonist; inhibits [125I]iodo-VIP binding and selectively inhibits VIP- and GRF-induced effects on adenylyl cyclase.

Technical Data

M. Wt 3475
Formula C157H252N44O43S
Sequence YFDAIFTNSYRKVLGQLSARKLLQDIMSR

(Modifications: Tyr-1 = N-terminal Ac, Phe-2 = D-Phe, Arg-29 = C-terminal amide)
Storage Desiccate at -20°C
CAS Number 93965-89-0
PubChem ID 56841984
InChI Key ZADZHIQNEPVWIV-QSAFYHFUSA-N
Smiles CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(C)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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Keywords: [Ac-Tyr1,D-Phe2]GRF 1-29, amide (human), [Ac-Tyr1,D-Phe2]GRF 1-29, amide (human) supplier, VIP, antagonist, Vasoactive, Intestinal, Peptide, Receptors, VPAC, [Ac-Tyr1D-Phe2]GRF1-29, amide, (human), 1172, Tocris Bioscience

Citations for [Ac-Tyr1,D-Phe2]GRF 1-29, amide (human)

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