AC 45594

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Cat.No. 3043 - AC 45594 | C13H20O2 | CAS No. 13037-86-0
Description: SF-1 inverse agonist
Chemical Name: 4-(Heptyloxy)phenol
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature (2)

Biological Activity

Selective inverse agonist at the orphan nuclear receptor steroidogenic factor-1 (SF-1) (IC50= 50 - 100 nM). Displays no activity at estrogen, LRH-1, ROR, ERR or Nurr receptors. Inhibits SFRE-mediated transcription.

Technical Data

M. Wt 208.3
Formula C13H20O2
Storage Store at +4°C
Purity ≥99% (HPLC)
CAS Number 13037-86-0
PubChem ID 25641
InChI Key HZBABTUFXQLADL-UHFFFAOYSA-N
Smiles OC1=CC=C(OCCCCCCC)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 20.83 100
ethanol 20.83 100

Preparing Stock Solutions

The following data is based on the product molecular weight 208.3. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.8 mL 24 mL 48.01 mL
5 mM 0.96 mL 4.8 mL 9.6 mL
10 mM 0.48 mL 2.4 mL 4.8 mL
50 mM 0.1 mL 0.48 mL 0.96 mL

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References

References are publications that support the biological activity of the product.

Del Tredici et al (2008) Identification of the first synthetic steroidogenic factor 1 inverse agonist.: pharmacological modulation of steroidogenic enymes. Mol.Pharmacol. 73 900 PMID: 18055761


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Keywords: AC 45594, AC 45594 supplier, SF-1, inverse, agonists, Nuclear, Receptors, Steroidogenic, Factor-1, AC45594, Other, 3043, Tocris Bioscience

Citations for AC 45594

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