α-CGRP (human)

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Cat.No. 3012 - alpha-CGRP (human) | Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2 | CAS No. 90954-53-3
Description: CGRP receptor agonist
Datasheet
Citations
Reviews
Literature

Biological Activity

Endogenous calcitonin gene-related peptide receptor (CGRP) agonist.

Technical Data

M. Wt 3789.33
Formula C163H267N51O49S2
Sequence ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF

(Modifications: Phe-37 = C-terminal amide, Disulfide bridge between 2 - 7)

Storage Desiccate at -20°C
CAS Number 90954-53-3
PubChem ID 44563440
InChI Key JMJJWZFCOWFIBU-XJVRLEFXSA-N
Smiles [H]N[C@@H](C)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC1=O)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 0.50 mg/ml in water

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Poyner et al (2002) International union of pharmacology XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors. Pharmacol.Revs. 54 233


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Keywords: alpha-CGRP (human), alpha-CGRP (human) supplier, CGRP, receptor, agonists, Receptors, calcitonin, amylin, AMY, alpha-CGRP, (human), α-CGRP, a-CGRP, Calcitonin, and, Related, 3012, Tocris Bioscience

Citations for α-CGRP (human)

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Literature in this Area

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