α-CGRP (human)

Pricing Availability Delivery Time Qty
Cat.No. 3012 - alpha-CGRP (human) | Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2 | CAS No. 90954-53-3
Description: CGRP receptor agonist
Datasheet
Citations
Literature

Biological Activity

Endogenous calcitonin gene-related peptide receptor (CGRP) agonist.

Technical Data

M. Wt 3789.33
Formula C163H267N51O49S2
Sequence ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF

(Modifications: Phe-37 = C-terminal amide, Disulfide bridge between 2 - 7)

Storage Desiccate at -20°C
CAS Number 90954-53-3
PubChem ID 44563440
InChI Key JMJJWZFCOWFIBU-XJVRLEFXSA-N
Smiles [H]N[C@@H](C)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC1=O)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 0.50 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 3789.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.26 mL 1.32 mL 2.64 mL
5 mM 0.05 mL 0.26 mL 0.53 mL
10 mM 0.03 mL 0.13 mL 0.26 mL
50 mM 0.01 mL 0.03 mL 0.05 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Poyner et al (2002) International union of pharmacology XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors. Pharmacol.Revs. 54 233 PMID:


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Keywords: alpha-CGRP (human), supplier, CGRP, receptor, agonists, Receptors, calcitonin, amylin, AMY, alpha-CGRP, (human), α-CGRP, a-CGRP, Calcitonin, and, Related, Receptors, Calcitonin, and, Related, Receptors, Tocris Bioscience

Citations for α-CGRP (human)

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