Discontinued ProductUnfortunately A-5 hydrochloride (Cat. No. 0377) has been withdrawn from sale for commercial reasons.
Calmodulin antagonist (inhibits calmodulin-activated PDE activity with an IC50 of 66 μM).
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 349.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.86 mL||14.32 mL||28.63 mL|
|5 mM||0.57 mL||2.86 mL||5.73 mL|
|10 mM||0.29 mL||1.43 mL||2.86 mL|
|50 mM||0.06 mL||0.29 mL||0.57 mL|
References are publications that support the products' biological activity.
Hidaka et al (1981) N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation. Proc.Natl.Acad.Sci.U.S.A. 78 4354 PMID: 6945588
Itoh and Hidaka (1984) Direct interaction of calmodulin antagonists with Ca2+/calmodulin-dependent cyclic nucleotide phosphodiesterase. J.Biochem. 96 1721 PMID: 6099352
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Keywords: A-5 hydrochloride, supplier, Calcium, Binding, Protein, Calcium, Binding, Protein, Tocris Bioscience
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