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Submit ReviewA-5 hydrochloride
Description: Calmodulin antagonist
Chemical Name: N-(4-Aminobutyl)-5-chloro-1-naphthalenesulfonamide hydrochloride
Biological Activity for A-5 hydrochloride
Calmodulin antagonist (inhibits calmodulin-activated PDE activity with an IC50 of 66 μM).
Technical Data for A-5 hydrochloride
| M. Wt | 349.27 |
| Storage | Store at RT |
| CAS Number | 78957-84-3 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for A-5 hydrochloride
Certificate of Analysis is currently unavailable on-line.
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References for A-5 hydrochloride
References are publications that support the biological activity of the product.
Hidaka et al (1981) N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation. Proc.Natl.Acad.Sci.U.S.A. 78 4354 PMID: 6945588
Itoh and Hidaka (1984) Direct interaction of calmodulin antagonists with Ca2+/calmodulin-dependent cyclic nucleotide phosphodiesterase. J.Biochem. 96 1721 PMID: 6099352
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