A-3 hydrochloride

Discontinued Product

A-3 hydrochloride (Cat. No. 0366) has been withdrawn from sale for commercial reasons.
Description: Protein kinase inhibitor
Chemical Name: N-(2-Aminoethyl)-5-chloro-1-naphthalenesulfonamide hydrochloride
Datasheet
Citations
Reviews
Literature (2)

Biological Activity for A-3 hydrochloride

Protein kinase inhibitor. Ki values are 4.3, 3.8, 7, 47, 80 and 5.1 μM for PKA, PKG, MLCK, PKC, casein kinase I and casein kinase II respectively.

Technical Data for A-3 hydrochloride

M. Wt 321.22
Formula C12H13ClN2O2S.HCl
Storage Store at RT
Smiles Cl.NCCNS(=O)(=O)c1c2cccc(Cl)c2ccc1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for A-3 hydrochloride

References for A-3 hydrochloride

References are publications that support the biological activity of the product.

Hidaka and Koybashi (1992) Pharmacology of protein kinase inhibitors. Annu.Rev.Pharmacol.Toxicol. 32 377 PMID: 1605572

Hidaka and Tanaka (1983) Naphthalenesulfonamides as calmodulin antagonists. Methods Enzymol. 102 185 PMID: 6139736

Hidaka and Hagiwara (1987) Pharmacology of the isoquinolinesulfonamide protein kinase C inhibitors. Trends Pharmacol.Sci. 8 162

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Citations for A-3 hydrochloride

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