A-3 hydrochloride

Cat. No. 0366 Datasheet / COA / SDS

Discontinued Product

Unfortunately A-3 hydrochloride (Cat. No. 0366) has been withdrawn from sale for commercial reasons.
Cat.No. 0366 - A-3 hydrochloride | C12H13ClN2O2S.HCl
Description: Protein kinase inhibitor
Chemical Name: N-(2-Aminoethyl)-5-chloro-1-naphthalenesulfonamide hydrochloride
Datasheet
Citations
Reviews
Literature

Biological Activity

Protein kinase inhibitor. Ki values are 4.3, 3.8, 7, 47, 80 and 5.1 μM for PKA, PKG, MLCK, PKC, casein kinase I and casein kinase II respectively.

Technical Data

M. Wt 321.22
Formula C12H13ClN2O2S.HCl
Storage Store at RT
Smiles Cl.NCCNS(=O)(=O)c1c2cccc(Cl)c2ccc1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Hidaka and Koybashi (1992) Pharmacology of protein kinase inhibitors. Annu.Rev.Pharmacol.Toxicol. 32 377 PMID: 1605572

Hidaka and Tanaka (1983) Naphthalenesulfonamides as calmodulin antagonists. Methods Enzymol. 102 185 PMID: 6139736

Hidaka and Hagiwara (1987) Pharmacology of the isoquinolinesulfonamide protein kinase C inhibitors. Trends Pharmacol.Sci. 8 162 PMID:

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Citations for A-3 hydrochloride

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