4-PPBP maleate

Pricing Availability   Qty
Cat.No. 0620 - 4-PPBP maleate | C21H27N.C4H4O4 | CAS No. 201216-39-9
Description: Specific σ ligand, NMDA antagonist
Chemical Name: 4-Phenyl-1-(4-phenylbutyl)piperidine maleate
Purity: ≥99% (HPLC)
Datasheet
Citations (1)
Reviews

Biological Activity for 4-PPBP maleate

4-PPBP maleate is a σ ligand and selective non-competitive antagonist at recombinant NR1a/2B NMDA receptors expressed in Xenopus oocytes.

Technical Data for 4-PPBP maleate

M. Wt 409.52
Formula C21H27N.C4H4O4
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 201216-39-9
PubChem ID 11682970
InChI Key OASPNIMFGJVLES-BTJKTKAUSA-N
Smiles OC(=O)\C=C/C(O)=O.C(CCC1=CC=CC=C1)CN1CCC(CC1)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for 4-PPBP maleate

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
ethanol 10.24 25
DMSO 10.24 25

Preparing Stock Solutions for 4-PPBP maleate

The following data is based on the product molecular weight 409.52. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.25 mM 9.77 mL 48.84 mL 97.68 mL
1.25 mM 1.95 mL 9.77 mL 19.54 mL
2.5 mM 0.98 mL 4.88 mL 9.77 mL
12.5 mM 0.2 mL 0.98 mL 1.95 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets for 4-PPBP maleate

References for 4-PPBP maleate

References are publications that support the biological activity of the product.

Glennon et al (1991) Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high affinity σ ligands. J.Med.Chem. 34 3360 PMID: 1662725

Whittemore et al (1997) Antagonism of N-MthD.-aspartate receptors by σ site ligands: potency, subtype-selectivity and mechanisms of inhibition. J.Pharmacol.Exp.Ther. 282 326 PMID: 9223571


If you know of a relevant reference for 4-PPBP maleate, please let us know.

View Related Products by Target

View Related Products by Product Action

View all Sigma-Related Ligands

Keywords: 4-PPBP maleate, 4-PPBP maleate supplier, Specific, σ, sigma, ligand, NMDA, antagonists, Receptors, Sigma-Related, 0620, Tocris Bioscience

1 Citation for 4-PPBP maleate

Citations are publications that use Tocris products. Selected citations for 4-PPBP maleate include:

Yang et al (2007) σ receptor agonists provide neuroprotection in vitro by preserving bcl-2. Front Behav Neurosci 104 1179 PMID: 17456670


Do you know of a great paper that uses 4-PPBP maleate from Tocris? Please let us know.

Reviews for 4-PPBP maleate

There are currently no reviews for this product. Be the first to review 4-PPBP maleate and earn rewards!

Have you used 4-PPBP maleate?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review