Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit Review3'-Fluorobenzylspiperone maleate
Description: D2-like receptor ligand
Chemical Name: 8-[4-(4-Fluorophenyl)-4-oxobutyl]-(3-fluorobenzyl-1-phenyl)-1,3,8-triazaspiro[4,5]decan-4-one maleate
Purity: ≥98% (HPLC)
Biological Activity for 3'-Fluorobenzylspiperone maleate
3'-Fluorobenzylspiperone maleate is a very potent and selective ligand for the D2 receptor (Ki = 0.023 nM). Compared with spiperone, displays a 2.5-fold greater affinity at D2 and a 12-fold lower affinity at 5-HT2 receptors.
Technical Data for 3'-Fluorobenzylspiperone maleate
| M. Wt | 619.67 |
| Formula | C30H31F2N3O2.C4H4O4 |
| Storage | Store at RT |
| Purity | ≥98% (HPLC) |
| CAS Number | 1135278-61-3 |
| PubChem ID | 24978532 |
| InChI Key | JURUFADWVGXLOY-BTJKTKAUSA-N |
| Smiles | OC(=O)\C=C/C(O)=O.FC1=CC=C(C=C1)C(=O)CCCN1CCC2(CC1)N(CN(CC1=CC=CC(F)=C1)C2=O)C1=CC=CC=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for 3'-Fluorobenzylspiperone maleate
References for 3'-Fluorobenzylspiperone maleate
References are publications that support the biological activity of the product.
Mach et al (1992) Effect of N-alkylation on the affinities of analogues of spiperone for DA D2 and serotonin 5-HT2 receptors. J.Med.Chem. 35 423 PMID: 1531364
View Related Products by Target
View Related Products by Product Action
Keywords: 3'-Fluorobenzylspiperone maleate, 3'-Fluorobenzylspiperone maleate supplier, D2-like, ligand, Dopamine, Non-Selective, Receptors, dopaminergic, 3-Fluorobenzylspiperone, maleate, Non-selective, 0701, Tocris Bioscience
Citations for 3'-Fluorobenzylspiperone maleate
Citations are publications that use Tocris products.
Currently there are no citations for 3'-Fluorobenzylspiperone maleate.
Reviews for 3'-Fluorobenzylspiperone maleate
There are currently no reviews for this product. Be the first to review 3'-Fluorobenzylspiperone maleate and earn rewards!
Have you used 3'-Fluorobenzylspiperone maleate?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Dopamine Receptors Scientific Review
Written by Phillip Strange and revised by Kim Neve in 2013, this review summarizes the history of the dopamine receptors and provides an overview of individual receptor subtype properties, their distribution and identifies ligands which act at each receptor subtype. Compounds available from Tocris are listed.
Parkinson's Disease Poster
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.