A very potent and selective ligand for the D2 receptor (Ki = 0.023 nM). Compared with spiperone, displays a 2.5-fold greater affinity at D2 and a 12-fold lower affinity at 5-HT2 receptors.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 619.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.61 mL||8.07 mL||16.14 mL|
|5 mM||0.32 mL||1.61 mL||3.23 mL|
|10 mM||0.16 mL||0.81 mL||1.61 mL|
|50 mM||0.03 mL||0.16 mL||0.32 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Mach et al (1992) Effect of N-alkylation on the affinities of analogues of spiperone for dopamine D2 and serotonin 5-HT2 receptors. J.Med.Chem. 35 423 PMID: 1531364
If you know of a relevant reference for 3'-Fluorobenzylspiperone maleate, please let us know.
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Keywords: D2-like ligand Dopamine Non-Selective Receptors dopaminergic 3-Fluorobenzylspiperone maleate Non-selective Dopamine
Citations for 3'-Fluorobenzylspiperone maleate
Citations are publications that use Tocris products.
Currently there are no citations for 3'-Fluorobenzylspiperone maleate. Do you know of a great paper that uses 3'-Fluorobenzylspiperone maleate from Tocris? If so please let us know.
Literature in this Area
Dopamine Receptors Scientific Review
Written by Phillip Strange and revised by Kim Neve in 2013, this review summarizes the history of the dopamine receptors and provides an overview of individual receptor subtype properties, their distribution and identifies ligands which act at each receptor subtype. Compounds available from Tocris are listed.
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