You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for 3'-Fluorobenzylspiperone maleate
3'-Fluorobenzylspiperone maleate is a very potent and selective ligand for the D2 receptor (Ki = 0.023 nM). Compared with spiperone, displays a 2.5-fold greater affinity at D2 and a 12-fold lower affinity at 5-HT2 receptors.
Technical Data for 3'-Fluorobenzylspiperone maleate
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for 3'-Fluorobenzylspiperone maleate
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for 3'-Fluorobenzylspiperone maleate
The following data is based on the product molecular weight 619.67. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.25 mM||6.46 mL||32.28 mL||64.55 mL|
|1.25 mM||1.29 mL||6.46 mL||12.91 mL|
|2.5 mM||0.65 mL||3.23 mL||6.46 mL|
|12.5 mM||0.13 mL||0.65 mL||1.29 mL|
Product Datasheets for 3'-Fluorobenzylspiperone maleate
References for 3'-Fluorobenzylspiperone maleate
References are publications that support the biological activity of the product.
Mach et al (1992) Effect of N-alkylation on the affinities of analogues of spiperone for DA D2 and serotonin 5-HT2 receptors. J.Med.Chem. 35 423 PMID: 1531364
If you know of a relevant reference for 3'-Fluorobenzylspiperone maleate, please let us know.
View Related Products by Product Action
Keywords: 3'-Fluorobenzylspiperone maleate, 3'-Fluorobenzylspiperone maleate supplier, D2-like, ligand, Dopamine, Non-Selective, Receptors, dopaminergic, 3-Fluorobenzylspiperone, maleate, Non-selective, 0701, Tocris Bioscience
Citations for 3'-Fluorobenzylspiperone maleate
Citations are publications that use Tocris products.
Currently there are no citations for 3'-Fluorobenzylspiperone maleate. Do you know of a great paper that uses 3'-Fluorobenzylspiperone maleate from Tocris? Please let us know.
Reviews for 3'-Fluorobenzylspiperone maleate
There are currently no reviews for this product. Be the first to review 3'-Fluorobenzylspiperone maleate and earn rewards!
Have you used 3'-Fluorobenzylspiperone maleate?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Dopamine Receptors Scientific Review
Written by Phillip Strange and revised by Kim Neve in 2013, this review summarizes the history of the dopamine receptors and provides an overview of individual receptor subtype properties, their distribution and identifies ligands which act at each receptor subtype. Compounds available from Tocris are listed.
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.
Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.