Home / Pharmacology / GPCRs / 7-TM Receptors / Adrenergic Receptors / Adrenergic α1 Receptors / Adrenergic α1 Receptor Ligands / 3-[2-[4-(2-Chlorophenyl)piperazin-1-yl]ethyl]pyrimido[5,4-b]indole-2,4-dione

3-[2-[4-(2-Chlorophenyl)piperazin-1-yl]ethyl]pyrimido[5,4-b]indole-2,4-dione

Cat. No. 0451 Submit a Review Datasheet / COA / SDS

Discontinued Product

3-[2-[4-(2-Chlorophenyl)piperazin-1-yl]ethyl]pyrimido[5,4-b]indole-2,4-dione (Cat. No. 0451) has been withdrawn from sale for commercial reasons.
Description: a1 ligand and s2 ligand
Datasheet
Citations
Reviews
Literature (4)
Biological Activity Technical Data Datasheets References

Biological Activity

Potent and extremely selective ligand for α1 sites (Ki = 0.5 nM). At least 200,000-fold selective for α1 over α2, β2 or 5-HT1A receptors.

Technical Data

M. Wt 423.9
Storage Store at RT
CAS Number 133399-68-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service
Safety Datasheet

References

References are publications that support the biological activity of the product.

Russo et al (1991) Pyrimido[5,4-b]indole derivatives. 1. A new class of potent and selective α1 adrenoceptor ligands. J.Med.Chem. 34 1850 PMID: 1648138

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Keywords: 3-[2-[4-(2-Chlorophenyl)piperazin-1-yl]ethyl]pyrimido[5,4-b]indole-2,4-dione, 3-[2-[4-(2-Chlorophenyl)piperazin-1-yl]ethyl]pyrimido[5,4-b]indole-2,4-dione supplier, Adrenergic, Alpha-1, Receptors, 0451, Tocris Bioscience

Citations for 3-[2-[4-(2-Chlorophenyl)piperazin-1-yl]ethyl]pyrimido[5,4-b]indole-2,4-dione

Citations are publications that use Tocris products.

Currently there are no citations for 3-[2-[4-(2-Chlorophenyl)piperazin-1-yl]ethyl]pyrimido[5,4-b]indole-2,4-dione.

Reviews for 3-[2-[4-(2-Chlorophenyl)piperazin-1-yl]ethyl]pyrimido[5,4-b]indole-2,4-dione

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Literature in this Area

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