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Submit Review(1R,3S)-ACPD
Discontinued Product
0299 has been discontinued.
View all Non-selective Metabotropic Glutamate products.
Description: Inactive isomer of trans-ACPD (0187)
Chemical Name: (1R,3S)-1-Aminocyclopentane-1,3-dicarboxylic acid
Biological Activity for (1R,3S)-ACPD
Inactive isomer of trans-ACPD at metabotropic glutamate receptors.
Technical Data for (1R,3S)-ACPD
| M. Wt | 173.17 |
| Storage | Desiccate at RT |
| CAS Number | 89253-38-3 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for (1R,3S)-ACPD
Certificate of Analysis is currently unavailable on-line.
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References for (1R,3S)-ACPD
References are publications that support the biological activity of the product.
Irving et al (1990) 1S,3R-ACPD stimulates and L-AP3 blocks Ca2+ mobilization in rat cerebellar neurons. Eur.J.Pharmacol. 186 363 PMID: 2289537
Mistry and Challiss (1996) Differences in agonist and antagonist activities for two indicies of metabotropic glutamate receptor-stimulated phosphoinositide turnover. Br.J.Pharmacol. 117 1735 PMID: 8732284
Nakanishi (1992) Molecular diversity of glutamate receptors and implications for brain functions. Science 258 597 PMID: 1329206
Sunter et al (1991) Actions of the four isomers of 1-aminocyclopentane-1,3-dicarboxylate (ACPD) in the hemisected spinal cord of the neonatal rat. Br.J.Pharmacol. 104 337P
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Keywords: (1R,3S)-ACPD, (1R,3S)-ACPD supplier, Non-selective, mGlu, 0299, Tocris Bioscience
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Metabotropic Glutamate Receptors Scientific Review
Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.
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