Discontinued Product

(1R,3S)-ACPD (Cat. No. 0299) has been withdrawn from sale for commercial reasons.
Description: Inactive isomer of trans-ACPD (0187)
Chemical Name: (1R,3S)-1-Aminocyclopentane-1,3-dicarboxylic acid
Literature (2)

Biological Activity for (1R,3S)-ACPD

Inactive isomer of trans-ACPD at metabotropic glutamate receptors.

Technical Data for (1R,3S)-ACPD

M. Wt 173.17
Storage Desiccate at RT
CAS Number 89253-38-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for (1R,3S)-ACPD

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service

References for (1R,3S)-ACPD

References are publications that support the biological activity of the product.

Irving et al (1990) 1S,3R-ACPD stimulates and L-AP3 blocks Ca2+ mobilization in rat cerebellar neurons. Eur.J.Pharmacol. 186 363 PMID: 2289537

Mistry and Challiss (1996) Differences in agonist and antagonist activities for two indicies of metabotropic glutamate receptor-stimulated phosphoinositide turnover. Br.J.Pharmacol. 117 1735 PMID: 8732284

Nakanishi (1992) Molecular diversity of glutamate receptors and implications for brain functions. Science 258 597 PMID: 1329206

Sunter et al (1991) Actions of the four isomers of 1-aminocyclopentane-1,3-dicarboxylate (ACPD) in the hemisected spinal cord of the neonatal rat. Br.J.Pharmacol. 104 337P

Keywords: (1R,3S)-ACPD, (1R,3S)-ACPD supplier, Non-selective, mGlu, 0299, Tocris Bioscience

Citations for (1R,3S)-ACPD

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Currently there are no citations for (1R,3S)-ACPD.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Metabotropic Glutamate Receptors Scientific Review

Metabotropic Glutamate Receptors Scientific Review

Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.

Parkinson's Disease Poster

Parkinson's Disease Poster

Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.