Discontinued Product

Unfortunately (1R,3S)-ACPD (Cat. No. 0299) has been withdrawn from sale for commercial reasons.
Cat.No. 0299 - (1R,3S)-ACPD | CAS No. 89253-38-3
Description: Inactive isomer of trans-ACPD (0187)
Chemical Name: (1R,3S)-1-Aminocyclopentane-1,3-dicarboxylic acid

Biological Activity

Inactive isomer of trans-ACPD at metabotropic glutamate receptors.

Technical Data

M. Wt 173.17
Storage Desiccate at RT
CAS Number 89253-38-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 173.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.77 mL 28.87 mL 57.75 mL
5 mM 1.15 mL 5.77 mL 11.55 mL
10 mM 0.58 mL 2.89 mL 5.77 mL
50 mM 0.12 mL 0.58 mL 1.15 mL

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Product Datasheets

Certificate of Analysis is currently unavailable on-line.
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Safety Datasheet


References are publications that support the products' biological activity.

Irving et al (1990) 1S,3R-ACPD stimulates and L-AP3 blocks Ca2+ mobilization in rat cerebellar neurons. Eur.J.Pharmacol. 186 363 PMID: 2289537

Mistry and Challiss (1996) Differences in agonist and antagonist activities for two indicies of metabotropic glutamate receptor-stimulated phosphoinositide turnover. Br.J.Pharmacol. 117 1735 PMID: 8732284

Nakanishi (1992) Molecular diversity of glutamate receptors and implications for brain functions. Science 258 597 PMID: 1329206

Sunter et al (1991) Actions of the four isomers of 1-aminocyclopentane-1,3-dicarboxylate (ACPD) in the hemisected spinal cord of the neonatal rat. Br.J.Pharmacol. 104 337P PMID:

Keywords: (1R,3S)-ACPD, supplier, Non-selective, mGlu, Non-selective, mGlu, Tocris Bioscience

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