1-Phenylbiguanide hydrochloride

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Cat.No. 0969 - 1-Phenylbiguanide hydrochloride | C8H11N5.HCl | CAS No. 55-57-2
Description: 5-HT3 agonist
Literature (2)

Biological Activity for 1-Phenylbiguanide hydrochloride

1-Phenylbiguanide hydrochloride is a 5-HT3 receptor agonist.

Technical Data for 1-Phenylbiguanide hydrochloride

M. Wt 213.67
Formula C8H11N5.HCl
Storage Store at RT
CAS Number 55-57-2
PubChem ID 5932
Smiles Cl.NC(=N)NC(=N)NC1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for 1-Phenylbiguanide hydrochloride

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 5.34 25

Preparing Stock Solutions for 1-Phenylbiguanide hydrochloride

The following data is based on the product molecular weight 213.67. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.25 mM 18.72 mL 93.6 mL 187.2 mL
1.25 mM 3.74 mL 18.72 mL 37.44 mL
2.5 mM 1.87 mL 9.36 mL 18.72 mL
12.5 mM 0.37 mL 1.87 mL 3.74 mL

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Product Datasheets for 1-Phenylbiguanide hydrochloride

Certificate of Analysis is currently unavailable on-line.
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References for 1-Phenylbiguanide hydrochloride

References are publications that support the biological activity of the product.

Ireland and Tyer (1987) Pharmacological characterization of 5-hydroxytryptamine induced depolarization of the rat isolated vagus nerve. Br.J.Pharmacol. 90 229 PMID: 3814920

If you know of a relevant reference for 1-Phenylbiguanide hydrochloride, please let us know.

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Keywords: 1-Phenylbiguanide hydrochloride, 1-Phenylbiguanide hydrochloride supplier, 5-HT3, agonists, Serotonin, Receptors, 0969, Tocris Bioscience

Citations for 1-Phenylbiguanide hydrochloride

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5-HT Receptors Scientific Review

Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.