1-Phenylbiguanide hydrochloride

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Cat.No. 0969 - 1-Phenylbiguanide hydrochloride | C8H11N5.HCl | CAS No. 55-57-2
Description: 5-HT3 agonist

Biological Activity

5-HT3 receptor agonist.

Technical Data

M. Wt 213.67
Formula C8H11N5.HCl
Storage Store at RT
CAS Number 55-57-2
PubChem ID 5932
Smiles Cl.NC(=N)NC(=N)NC1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 5.34 25

Preparing Stock Solutions

The following data is based on the product molecular weight 213.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.68 mL 23.4 mL 46.8 mL
5 mM 0.94 mL 4.68 mL 9.36 mL
10 mM 0.47 mL 2.34 mL 4.68 mL
50 mM 0.09 mL 0.47 mL 0.94 mL

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Product Datasheets

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service
Safety Datasheet


References are publications that support the products' biological activity.

Ireland and Tyer (1987) Pharmacological characterization of 5-hydroxytryptamine induced depolarization of the rat isolated vagus nerve. Br.J.Pharmacol. 90 229 PMID: 3814920

If you know of a relevant reference for 1-Phenylbiguanide hydrochloride, please let us know.

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Literature in this Area

5-HT Receptors

5-HT Receptors Scientific Review

Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.