Selective inhibitor of α-mannosidase I.
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 199.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||5.01 mL||25.05 mL||50.09 mL|
|5 mM||1 mL||5.01 mL||10.02 mL|
|10 mM||0.5 mL||2.5 mL||5.01 mL|
|50 mM||0.1 mL||0.5 mL||1 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Bischoff et al (1986) The use of 1-deoxymannojirimycin to evaluate the role of various α-mannosidases in oligosaccharide processing in intact cells. J.Biol.Chem. 261 4766 PMID: 2937779
Bischoff and Kornfeld (1984) The effect of 1-deoxymannojirimycin on rat liver α-mannosidases. Biochem.Biophys.Res.Commun. 125 324 PMID: 6239623
Fuhrmann et al (1984) Novel mannosidase inhibitor blocking conversion of high mannose to complex oligosaccharides. Nature 307 755 PMID: 6230538
If you know of a relevant reference for 1-Deoxymannojirimycin hydrochloride, please let us know.
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Keywords: α-mannosidase alpha-mannosidase I inhibitors inhibits a-Mannosidase Glycosylases Carbohydrate Metabolism antibiotics Glycosylases
1 Citation for 1-Deoxymannojirimycin hydrochloride
Citations are publications that use Tocris products. Selected citations for 1-Deoxymannojirimycin hydrochloride include:
Tareen et al (2014) Design of a novel integration-deficient lentivector technology that incorporates genetic and posttranslational elements to target human dendritic cells. Mol Ther 22 575 PMID: 24419083
Do you know of a great paper that uses 1-Deoxymannojirimycin hydrochloride from Tocris? If so please let us know.
Literature in this Area
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