Thyrotropin-Releasing Hormone Receptors

Thyrotropin-releasing hormone (TRH) receptors are G_q/11-protein-coupled receptors that promote thyroid-stimulating hormone (TSH) and prolactin (PRL) release. Two TRH receptor subtypes, TRH₁ and TRH₂, have been identified in rodents, but only the TRH₁ receptor has been found in humans. TRH₁ is predominantly expressed in the anterior pituitary gland, but is also found at appreciable levels in the brain, pancreas, testis, adrenals and lymphoid organs. The human gene encoding the TRH₁ receptor is located on chromosome 8q23.1.

External sources of pharmacological information for Thyrotropin-Releasing Hormone Receptors :

• IUPHAR Receptor Code

• BJP Guide

Literature for Thyrotropin-Releasing Hormone Receptors

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GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

• Rhodopsin-like Receptors
• Secretin-like Receptors
• Glutamate Receptors
• Frizzled Receptors
• GPCR Signaling

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Peptide Hormone Receptors Product Listing

A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:

• Anterior Pituitary Regulation
• Blood Pressure Regulation
• Feeding and Appetite Regulation
• Glucose Regulation
• Peptide Hormone Processing

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Thyrotropin-Releasing Hormone Receptor Gene Data