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Thyrotropin-Releasing Hormone Receptors

Thyrotropin-releasing hormone (TRH) receptors are Gq/11-protein-coupled receptors that promote thyroid-stimulating hormone (TSH) and prolactin (PRL) release. Two TRH receptor subtypes, TRH1 and TRH2, have been identified in rats but only TRH1 has been found in humans.

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Background
Literature (2)
Gene Data

Agonists
Cat. No. Product Name / Activity
2672 Taltirelin
Synthetic thyrotropin-releasing hormone analog

Thyrotropin-releasing hormone (TRH) receptors are Gq/11-protein-coupled receptors that promote thyroid-stimulating hormone (TSH) and prolactin (PRL) release. Two TRH receptor subtypes, TRH1 and TRH2, have been identified in rodents, but only the TRH1 receptor has been found in humans. TRH1 is predominantly expressed in the anterior pituitary gland, but is also found at appreciable levels in the brain, pancreas, testis, adrenals and lymphoid organs. The human gene encoding the TRH1 receptor is located on chromosome 8q23.1.

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Literature for Thyrotropin-Releasing Hormone Receptors

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GPCR

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

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Peptide Hormone Receptors

Peptide Hormone Receptors Product Listing

A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:

  • Anterior Pituitary Regulation
  • Blood Pressure Regulation
  • Feeding and Appetite Regulation
  • Glucose Regulation
  • Peptide Hormone Processing

Thyrotropin-Releasing Hormone Receptor Gene Data

Species Gene Symbol Gene Accession No. Protein Accession No.
Human TRHR NM_003301 P34981
Mouse Trhr NM_013696 P21761
Rat Trhr NM_013047 Q01717