Cat. No. 2918
Chemical Name: 4α,9-Epoxy-3β-veratroyloxy-5β-cevan-4β,
Biological ActivityVoltage-gated Na+ channel opener; increases intracellular Ca2+ with no effect on the Na+/Ca2+ exchanger. Steroid-derived alkaloid neurotoxin. Increases membrane Na+ permeability and depolarizes excitable tissues.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Fekete et al (2009) Mechanism of the persistant sodium current activator veratridine-evoked Ca2+ elevation: implication for epilepsy. J.Neurochem. 111 745. PMID: 19719824.
Maroto et al (1994) Effects of Ca2+ channel antagonists on chromaffin cell death and cytosolic Ca2+ oscillations induced by veratridine. Eur.J.Pharmacol. 270 331. PMID: 7805782.
McKinney et al (1986) Purification, solubility and pKa of veratridine. Anal.Biochem. 153 33. PMID: 3963380.
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Keywords: Veratridine, supplier, Sodium, channel, opener, neutoxin, Na+, Na, voltage-gated, ion, channels, neurotoxins, Tocris Bioscience, Voltage-gated Sodium (NaV) Channel Activator products
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