Cat. No. 3550
Chemical Name: N-Acetyl-5-methoxytryptamine
Biological ActivityEndogenous hormone that acts as an agonist at melatonin receptors MT1 and MT2. Exhibits a prominent role in the control of circadian rhythm, displays immunomodulatory activity and acts as a powerful antioxidant in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Cardinali et al (2009) Melatonin and melatonergic drugs on sleep: possible mechanisms of action. Int.J.Neurosci. 119 821. PMID: 19326288.
Bubenik (2008) Thirty four years since the discovery of gastrointestinal melatonin. J.Physiol.Pharmacol. 59 33. PMID: 18812627.
Fischer et al (2008) Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair. Exp.Dermatol. 17 713. PMID: 18643846.
If you know of a relevant reference for Melatonin please let us know.
Citations are publications that use Tocris products. Selected citations for Melatonin include:
Chen et al (2014) Antinociceptive effects of novel melatonin receptor agonists in mouse models of abdominal pain. Toxicol Sci 20 1298. PMID: 24574803.
Huang et al (2010) Comparative cytotoxicity and intracellular accumulation of five polybrominated diphenyl ether congeners in mouse cerebellar granule neurons. Nature 114 124. PMID: 19969594.
Do you know of a great paper that uses Melatonin from Tocris? If so please let us know.
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Keywords: Melatonin, supplier, Endogenous, hormone, agonists, MT1, MT2, Receptors, Melatonin, circadian, rhythms, Tocris Bioscience, Melatonin Receptor Agonist products
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