Cat. No. 0285
Chemical Name: α-Amino-(3-hydroxy-5-isoxazolyl)acet
Biological ActivityNMDA and metabotropic glutamate receptor agonist.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Pin and Duvoisin (1995) The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34 1. PMID: 7623957.
Nakanishi (1992) Molecular diversity of glutamate receptors and implications for brain functions. Science 258 597. PMID: 1329206.
Watkins and Evans (1981) Excitatory amino acid transmitters. Annu.Rev.Pharmacol.Toxicol. 21 165. PMID: 6112965.
Johnston et al (1968) Central actions of ibotenic acid and muscimol. Biochem.Pharmacol. 17 2488. PMID: 5752907.
If you know of a relevant reference for Ibotenic acid please let us know.
Citations are publications that use Tocris products. Selected citations for Ibotenic acid include:
Renouard et al (2015) The supramammillary nucleus and the claustrum activate the cortex during REM sleep. Neurobiol Learn Mem 1 e1400177. PMID: 26601158.
Karlsson et al (2013) Exaggerated cue-induced reinstatement of cocaine seeking but not incubation of cocaine craving in a developmental rat model of schizophrenia. Psychopharmacology (Berl) 226 45. PMID: 23010798.
Pitts and Takahashi (2011) The central amygdala nucleus via corticotropin-releasing factor is necessary for time-limited consolidation processing but not storage of contextual fear memory. Neuroreport 95 86. PMID: 21093597.
Do you know of a great paper that uses Ibotenic acid from Tocris? If so please let us know.
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Keywords: Ibotenic acid, supplier, Non-Selective, NMDA, agonists, mGlur, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, Metabotropic, Tocris Bioscience, NMDA Receptor Agonist products
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