You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for ZQ 16
ZQ 16 is a selective medium-chain free fatty acid receptor GPR84 agonist (EC50 = 139 nM). Exhibits no response at GPR40, GPR41, GPR119 or GPR120 at 100 μM. Activates calcium mobilization, inhibits cAMP accumulation, and induces ERK1/2 phosphorylation, receptor desensitization and internalization in vitro.
Technical Data for ZQ 16
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for ZQ 16
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for ZQ 16
The following data is based on the product molecular weight 228.31. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4.38 mL||21.9 mL||43.8 mL|
|5 mM||0.88 mL||4.38 mL||8.76 mL|
|10 mM||0.44 mL||2.19 mL||4.38 mL|
|50 mM||0.09 mL||0.44 mL||0.88 mL|
References for ZQ 16
References are publications that support the biological activity of the product.
Liu et al (2016) Design and synthesis of 2-alkylpyrimidine-4,6-diol and 6-alkylpyridine-2,4-diol as potent GPR84 agonists. ACS Med.Chem.Lett. 7 579 PMID: 27326330
Zhang et al (2016) Discovery and characterization of a novel small-molecule agonist for medium-chain free fatty acid receptor G protein-coupled receptor 84. J.Pharmacol.Exp.Ther. 357 337 PMID: 26962172
If you know of a relevant reference for ZQ 16, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: ZQ 16, ZQ 16 supplier, ZQ16, selective, medium, chain, free, fatty, acid, receptor, GPR84, agonists, agonism, Free, Fatty, Acid, Receptors, 6001, Tocris Bioscience
1 Citation for ZQ 16
Citations are publications that use Tocris products. Selected citations for ZQ 16 include:
Sundqvist (2018) Similarities and differences between the responses induced in human phagocytes through activation of the medium chain fatty acid receptor GPR84 and the short chain fatty acid receptor FFA2R. Biochim Biophys Acta 1865 695 PMID: 29477577
Do you know of a great paper that uses ZQ 16 from Tocris? Please let us know.
Reviews for ZQ 16
There are currently no reviews for this product. Be the first to review ZQ 16 and earn rewards!
Have you used ZQ 16?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.