YM 750

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Cat.No. 3039 - YM 750 | C31H36N2O | CAS No. 138046-43-2
Description: ACAT inhibitor
Chemical Name: N-Cycloheptyl-N-(9H-fluoren-2-ylmethyl)-N'-(2,4,6-trimethylphenyl)urea
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature (2)

Biological Activity

Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC50 = 0.18 μM). Exhibits hypocholesterolaemic and antiatherosclerotic activity in vivo.

Licensing Information

Sold with the permission of Astellas Pharma Inc.

Technical Data

M. Wt 452.63
Formula C31H36N2O
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 138046-43-2
PubChem ID 9911716
InChI Key FMLJREWZCZHGGW-UHFFFAOYSA-N
Smiles O=C(NC5=C(C)C=C(C)C=C5C)N(C4CCCCCC4)CC3=CC2=C(C=C3)C1=CC=CC=C1C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 45.26 100
ethanol 4.53 10

Preparing Stock Solutions

The following data is based on the product molecular weight 452.63. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.21 mL 11.05 mL 22.09 mL
5 mM 0.44 mL 2.21 mL 4.42 mL
10 mM 0.22 mL 1.1 mL 2.21 mL
50 mM 0.04 mL 0.22 mL 0.44 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Keywords: YM 750, YM 750 supplier, Acyl-CoA:cholesterol, acyltransferase, ACAT, inhibitors, inhibits, transferase, YM750, Acyl-CoA:Cholesterol, Acyltransferase, 3039, Tocris Bioscience

Citations for YM 750

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