Pricing Availability   Qty
Description: Adenosine receptor antagonist
Chemical Name: 2-[4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetic acid
Purity: ≥98% (HPLC)
Citations (1)

Biological Activity for XCC

XCC is an adenosine receptor antagonist (Ki values are 42, 68 and 1130 nM for A1, A2B and A2A receptors).

Technical Data for XCC

M. Wt 386.4
Formula C19H22N4O5
Storage Desiccate at RT
Purity ≥98% (HPLC)
CAS Number 96865-83-7
PubChem ID 126079
Smiles O=C1N(CCC)C(C(NC(C3=CC=C(OCC(O)=O)C=C3)=N2)=C2N1CCC)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for XCC

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 19.32 50

Preparing Stock Solutions for XCC

The following data is based on the product molecular weight 386.4. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 5.18 mL 25.88 mL 51.76 mL
2.5 mM 1.04 mL 5.18 mL 10.35 mL
5 mM 0.52 mL 2.59 mL 5.18 mL
25 mM 0.1 mL 0.52 mL 1.04 mL

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Product Datasheets for XCC

Certificate of Analysis / Product Datasheet
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References for XCC

References are publications that support the biological activity of the product.

Jarvis et al (1989) Autoradiographic characterization of high-affinity adenosine A2 receptors in the rat brain. Brain Res. 484 111 PMID: 2713675

Sebastiao et al (1990) The inhibitory adenosine receptor at the neuromuscular junction and hippocampus of the rat: antagonism by 1,3,8-substituted xanthines. Br.J.Pharmacol. 101 453 PMID: 2257444

Thummler and Dunwiddie (2000) Adenosine receptor antagonists induce persistent bursting in the rat hippocampal CA3 region via an NMDA receptor-dependent mechanism. J.Neurophysiol. 83 1787 PMID: 10758091

If you know of a relevant reference for XCC, please let us know.

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Keywords: XCC, XCC supplier, XCC, adenosine, antagonists, Non-selective, Adenosine, 4220, Tocris Bioscience

1 Citation for XCC

Citations are publications that use Tocris products. Selected citations for XCC include:

Wakisaka et al (2017) An Adenosine Receptor for Olfaction in Fish. Curr Biol 27 1437 PMID: 28502661

Do you know of a great paper that uses XCC from Tocris? Please let us know.

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