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Adenosine receptor antagonist (Ki values are 42, 68 and 1130 nM for A1, A2B and A2A receptors).
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 386.4. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||5.18 mL||25.88 mL||51.76 mL|
|2.5 mM||1.04 mL||5.18 mL||10.35 mL|
|5 mM||0.52 mL||2.59 mL||5.18 mL|
|25 mM||0.1 mL||0.52 mL||1.04 mL|
References are publications that support the biological activity of the product.
Jarvis et al (1989) Autoradiographic characterization of high-affinity adenosine A2 receptors in the rat brain. Brain Res. 484 111 PMID: 2713675
Sebastiao et al (1990) The inhibitory adenosine receptor at the neuromuscular junction and hippocampus of the rat: antagonism by 1,3,8-substituted xanthines. Br.J.Pharmacol. 101 453 PMID: 2257444
Thummler and Dunwiddie (2000) Adenosine receptor antagonists induce persistent bursting in the rat hippocampal CA3 region via an NMDA receptor-dependent mechanism. J.Neurophysiol. 83 1787 PMID: 10758091
If you know of a relevant reference for XCC, please let us know.
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Keywords: XCC, XCC supplier, XCC, adenosine, antagonists, Non-selective, Adenosine, 4220, Tocris Bioscience
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