You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
WL 47 - dimer
Discontinued ProductWL 47 - dimer (Cat. No. 5978) has been withdrawn from sale for commercial reasons.
Biological Activity for WL 47 - dimer
WL 47 - dimer is a high affinity caveolin-1 (CAV1) ligand (Kd = 23 nM); disrupts caveolin-1 oligomers. Exhibits selectivity for CAV1 over BSA, casein and HEWL.
Sold with kind permission of Professor Gregory Weiss
Technical Data for WL 47 - dimer
(Modifications: Disulfide Bridge = 1-1*)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References for WL 47 - dimer
References are publications that support the biological activity of the product.
Gilliam et al (2016) Affinity-Guided Design of Caveolin-1 Ligands for Deoligomerization. J.Med.Chem. 59 4019 PMID: 27010220
Keywords: WL 47 - dimer, WL 47 - dimer supplier, WL47, dimer, high, affinity, selective, caveolin-1, CAV1, ligands, oligomerization, disrupts, Translocation,, Exocytosis, &, Endocytosis, 5978, Tocris Bioscience
Citations for WL 47 - dimer
Citations are publications that use Tocris products.
Currently there are no citations for WL 47 - dimer.
Reviews for WL 47 - dimer
There are currently no reviews for this product. Be the first to review WL 47 - dimer and earn rewards!
Have you used WL 47 - dimer?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
GPCR Efficacy and Biased Agonism Poster
GPCRs can interact with multiple distinct transducers or regulatory proteins and these can be preferentially engaged in an agonist-specific manner giving rise to biased agonism. This poster discusses cutting edge GPCR signaling pharmacology and highlights therapeutic applications of biased agonism.
Coronavirus Research Brochure eBook
COVID-19 is a potentially fatal form of pneumonia that emerged in China in 2019. It is caused by a newly identified coronavirus termed SARS-CoV-2. This brochure provides an overview of our knowledge of the virus and highlights products available from Bio-Techne to enable research into finding a treatment, including:
- Antibodies, Recombinant Proteins, Small Molecules
- Cell Isolation and Identification Kits
- Tocriscreen Compound Libraries
- RNAscopeTM Assays