WL 47 - dimer

Pricing Availability Delivery Time Qty
Cat.No. 5978 - WL 47 - dimer | Lys-Leu-Arg-Met-Trp-Ser-Cys-Cys-Ser-Trp-Met-Arg-Leu-Lys
Description: High affinity caveolin-1 ligand
Datasheet
Citations
Literature

Biological Activity

High affinity caveolin-1 (CAV1) ligand (Kd = 23 nM); disrupts caveolin-1 oligomers. Exhibits selectivity for CAV1 over BSA, casein and HEWL.

Licensing Information

Sold with kind permission of Professor Gregory Weiss

Technical Data

M. Wt 1844.3
Formula C80H130N24O18S4
Sequence CSWMRLK CSWMRLK*

(Modifications: Disulfide Bridge = 1-1*)

Storage Store at -20°C
PubChem ID 123773278
InChI Key DNQUEMNLAOMZEO-HFXGPFCTSA-N
Smiles [H]N[C@@H](CSSC[C@H](N[H])C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 1 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 1844.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.54 mL 2.71 mL 5.42 mL
5 mM 0.11 mL 0.54 mL 1.08 mL
10 mM 0.05 mL 0.27 mL 0.54 mL
50 mM 0.01 mL 0.05 mL 0.11 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Gilliam et al (2016) Affinity-Guided Design of Caveolin-1 Ligands for Deoligomerization. J.Med.Chem. 59 4019 PMID: 27010220


If you know of a relevant reference for WL 47 - dimer, please let us know.

Keywords: WL 47 - dimer, supplier, WL47, dimer, high, affinity, selective, caveolin-1, CAV1, ligands, oligomerization, disrupts, Translocation,, Exocytosis, &, Endocytosis, Translocation,, Exocytosis, &, Endocytosis, Tocris Bioscience

Citations for WL 47 - dimer

Citations are publications that use Tocris products.

Currently there are no citations for WL 47 - dimer. Do you know of a great paper that uses WL 47 - dimer from Tocris? If so please let us know.

WL 47 - dimer Reviews

Average Rating:

(Based on 0 Reviews)


1 Star
0%
2 Star
0%
3 Star
0%
4 Star
0%
5 Star
0%

Have you used WL 47 - dimer?

Submit a review and receive a $25US/€18/£15/$25CAN Amazon gift card if you include an image -$10US/€7/£6/$10CAN Amazon gift card for reviews without an image. Limited to verified customers in USA, Canada and Europe.


Literature in this Area

Cancer

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis