WL 47 - dimer

Discontinued Product

WL 47 - dimer (Cat. No. 5978) has been withdrawn from sale for commercial reasons.
Description: High affinity caveolin-1 ligand
Literature (1)

Biological Activity for WL 47 - dimer

WL 47 - dimer is a high affinity caveolin-1 (CAV1) ligand (Kd = 23 nM); disrupts caveolin-1 oligomers. Exhibits selectivity for CAV1 over BSA, casein and HEWL.

Licensing Information

Sold with kind permission of Professor Gregory Weiss

Technical Data for WL 47 - dimer

M. Wt 1844.3
Formula C80H130N24O18S4

(Modifications: Disulfide Bridge = 1-1*)

Storage Store at -20°C
PubChem ID 123773278
Smiles [H]N[C@@H](CSSC[C@H](N[H])C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for WL 47 - dimer

References for WL 47 - dimer

References are publications that support the biological activity of the product.

Gilliam et al (2016) Affinity-Guided Design of Caveolin-1 Ligands for Deoligomerization. J.Med.Chem. 59 4019 PMID: 27010220

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Keywords: WL 47 - dimer, WL 47 - dimer supplier, WL47, dimer, high, affinity, selective, caveolin-1, CAV1, ligands, oligomerization, disrupts, Endocytosis, 5978, Tocris Bioscience

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Literature in this Area

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