VULM 1457

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Cat.No. 2988 - VULM 1457 | C25H27N3O3S | CAS No. 228544-65-8
Description: ACAT inhibitor
Chemical Name: N-[2,6-bis(1-Methylethyl)phenyl]-N'-[4-[(4-nitrophenyl)thio]phenyl]urea
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature (2)

Biological Activity

Acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor. Decreases cholesterol levels in the plasma and liver of diabetic-hypercholesterolemic rats.

Technical Data

M. Wt 449.57
Formula C25H27N3O3S
Storage Store at +4°C
Purity ≥99% (HPLC)
CAS Number 228544-65-8
PubChem ID 9933427
InChI Key XFFITGBWVLQNCD-UHFFFAOYSA-N
Smiles O=C(NC3=C(C(C)C)C=CC=C3C(C)C)NC(C=C2)=CC=C2SC1=CC=C([N+]([O-])=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 44.96 100

Preparing Stock Solutions

The following data is based on the product molecular weight 449.57. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.22 mL 11.12 mL 22.24 mL
5 mM 0.44 mL 2.22 mL 4.45 mL
10 mM 0.22 mL 1.11 mL 2.22 mL
50 mM 0.04 mL 0.22 mL 0.44 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Keywords: VULM 1457, VULM 1457 supplier, Acyl-CoA, cholesterol, acyltransferase, ACAT, inhibitors, inhibits, Transferases, VULM1457, Acyl-CoA:Cholesterol, Acyltransferase, 2988, Tocris Bioscience

Citations for VULM 1457

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