Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewVirodhamine
Discontinued Product
Virodhamine (Cat. No. 1569) has been withdrawn from sale for commercial reasons.
Description: GPR55 and CB2 agonist. CB1 partial agonist/antagonist
Alternative Names: O-Arachidonyl ethanolamine
Chemical Name: O-(2-Aminoethyl)-5Z,8Z,11Z,14Z-eicosatetraenoate
Biological Activity for Virodhamine
Endogenous cannabinoid receptor mixed agonist/antagonist found in higher concentrations peripherally than anandamide. Full agonist at GPR55 and CB2 and partial agonist/antagonist at CB1 (EC50 values are 12, 381 and 2920 nM at GPR55, CB2 and CB1 receptors respectively). Induces hypothermia in vivo.
Technical Data for Virodhamine
| M. Wt | 347.54 |
| Formula | C22H37NO2 |
| Storage | Desiccate at -20°C |
| CAS Number | 287937-12-6 |
| Smiles | O=C(OCCN)CCC\C=C/C\C=C/C/C=C\C/C=C\CCCCC |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Virodhamine
References for Virodhamine
References are publications that support the biological activity of the product.
Porter et al (2002) Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor. J.Pharmacol.Exp.Ther. 301 1020 PMID: 12023533
Ryberg et al (2007) The orphan receptor GPR55 is a novel cannabinoid receptor. Br.J.Pharmacol. 152 1092 PMID: 17876302
Sauer et al (2002) Further characterization of the novel endocannabinoid virodhamine. 2002 Symposium on the Cannabinoids, International
View Related Products by Target
View Related Products by Product Action
Keywords: Virodhamine, Virodhamine supplier, GPR55, CB2, agonists, CB1, partial, antagonists, non-selective, cannabinoids, receptors, cb2r, cb1r, O-Arachidonyl, ethanolamine, Non-selective, Cannabinoids, 1569, Tocris Bioscience
Citations for Virodhamine
Citations are publications that use Tocris products.
Currently there are no citations for Virodhamine.
Reviews for Virodhamine
There are currently no reviews for this product. Be the first to review Virodhamine and earn rewards!
Have you used Virodhamine?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
GPCR Product Listing
A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:
- Rhodopsin-like Receptors
- Glutamate Receptors
- Frizzled Receptors
- GPCR Signaling
Pain Research Product Guide
A collection of over 280 products for pain research, the guide includes research tools for the study of:
- Nociception
- Ion Channels
- G-Protein-Coupled Receptors
- Intracellular Signaling
Cannabinoid Receptor Ligands Scientific Review
Written by Roger Pertwee, this review discusses compounds which affect the activity of the endocannabinoid system, focusing particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.