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Endogenous cannabinoid receptor mixed agonist/antagonist found in higher concentrations peripherally than anandamide. Full agonist at GPR55 and CB2 and partial agonist/antagonist at CB1 (EC50 values are 12, 381 and 2920 nM at GPR55, CB2 and CB1 receptors respectively). Induces hypothermia in vivo. Also available as part of the Cannabinoid Receptor Agonist Tocriset™ and Endocannabinoid Tocriset™.
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Porter et al (2002) Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor. J.Pharmacol.Exp.Ther. 301 1020 PMID: 12023533
Ryberg et al (2007) The orphan receptor GPR55 is a novel cannabinoid receptor. Br.J.Pharmacol. 152 1092 PMID: 17876302
Sauer et al (2002) Further characterization of the novel endocannabinoid virodhamine. 2002 Symposium on the Cannabinoids, International
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Keywords: Virodhamine, Virodhamine supplier, GPR55, CB2, agonists, CB1, partial, antagonists, non-selective, cannabinoids, receptors, cb2r, cb1r, O-Arachidonyl, ethanolamine, Non-selective, Cannabinoids, 1569, Tocris Bioscience
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