Virodhamine trifluoroacetate

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Cat.No. 5395 - Virodhamine trifluoroacetate | C22H37NO2.CF3CO2H | CAS No. 1415264-56-0
Description: TFA salt of virodhamine, an endogenous cannabinoid receptor mixed agonist/antagonist
Chemical Name: O-(2-Aminoethyl)-5Z,8Z,11Z,14Z-eicosatetraenoate trifluoroacetate
Purity: ≥98% (HPLC)
Datasheet
Citations
Literature

Biological Activity

TFA salt of virodhamine, an endogenous cannabinoid receptor mixed agonist/antagonist that is found in higher concentrations peripherally than anandamide. Virodhamine is a full agonist at GPR55 and CB2 and partial agonist/antagonist at CB1 (EC50 values are 12, 381 and 2920 nM at GPR55, CB2 and CB1 receptors respectively).

Technical Data

M. Wt 461.56
Formula C22H37NO2.CF3CO2H
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 1415264-56-0
PubChem ID 91691131
InChI Key APQWCQIPZHJFAU-XVSDJDOKSA-N
Smiles O=C(OCCN)CCC\C=C/C\C=C/C/C=C\C/C=C\CCCCC.FC(F)(F)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 461.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.17 mL 10.83 mL 21.67 mL
5 mM 0.43 mL 2.17 mL 4.33 mL
10 mM 0.22 mL 1.08 mL 2.17 mL
50 mM 0.04 mL 0.22 mL 0.43 mL

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References

References are publications that support the products' biological activity.

Porter et al (2002) Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor. J.Pharmacol.Exp.Ther. 301 1020 PMID: 12023533


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Keywords: Virodhamine TFA GPR55 CB2 agonists CB1 partial antagonists non-selective cannabinoids receptors cb2r cb1r Trifluoroacetic acid salt Non-selective Cannabinoids

Citations for Virodhamine trifluoroacetate

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