Virodhamine trifluoroacetate

Discontinued Product

Virodhamine trifluoroacetate (Cat. No. 5395) has been withdrawn from sale for commercial reasons.
Description: TFA salt of virodhamine, an endogenous cannabinoid receptor mixed agonist/antagonist
Chemical Name: O-(2-Aminoethyl)-5Z,8Z,11Z,14Z-eicosatetraenoate trifluoroacetate
Purity: ≥98% (HPLC)
Citations (1)
Literature (1)

Biological Activity for Virodhamine trifluoroacetate

Virodhamine trifluoroacetate is a TFA salt of virodhamine, an endogenous cannabinoid receptor mixed agonist/antagonist that is found in higher concentrations peripherally than anandamide. Virodhamine is a full agonist at GPR55 and CB2 and partial agonist/antagonist at CB1 (EC50 values are 12, 381 and 2920 nM at GPR55, CB2 and CB1 receptors respectively).

Technical Data for Virodhamine trifluoroacetate

M. Wt 461.56
Formula C22H37NO2.CF3CO2H
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 1415264-56-0
PubChem ID 91691131

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Virodhamine trifluoroacetate

References for Virodhamine trifluoroacetate

References are publications that support the biological activity of the product.

Porter et al (2002) Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor. J.Pharmacol.Exp.Ther. 301 1020 PMID: 12023533

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1 Citation for Virodhamine trifluoroacetate

Citations are publications that use Tocris products. Selected citations for Virodhamine trifluoroacetate include:

Hayase (2013) Working memory- and anxiety-related behavioral effects of repeated nicotine as a stressor: the role of cannabinoid receptors. BMC Neurosci 14 20 PMID: 23394117

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Cannabinoid Receptor Ligands Scientific Review

Cannabinoid Receptor Ligands Scientific Review

Written by Roger Pertwee, this review discusses compounds which affect the activity of the endocannabinoid system, focusing particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.