Virodhamine trifluoroacetate
Biological Activity
TFA salt of virodhamine, an endogenous cannabinoid receptor mixed agonist/antagonist that is found in higher concentrations peripherally than anandamide. Virodhamine is a full agonist at GPR55 and CB2 and partial agonist/antagonist at CB1 (EC50 values are 12, 381 and 2920 nM at GPR55, CB2 and CB1 receptors respectively).
Technical Data
| M. Wt | 461.56 |
| Formula | C22H37NO2.CF3CO2H |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 1415264-56-0 |
| PubChem ID | 91691131 |
| InChI Key | APQWCQIPZHJFAU-XVSDJDOKSA-N |
| Smiles | O=C(OCCN)CCC\C=C/C\C=C/C/C=C\C/C=C\CCCCC.FC(F)(F)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Product Datasheets
References
References are publications that support the biological activity of the product.
Porter et al (2002) Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor. J.Pharmacol.Exp.Ther. 301 1020 PMID: 12023533
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1 Citation for Virodhamine trifluoroacetate
Citations are publications that use Tocris products. Selected citations for Virodhamine trifluoroacetate include:
Hayase (2013) Working memory- and anxiety-related behavioral effects of repeated nicotine as a stressor: the role of cannabinoid receptors. BMC Neurosci 14 20 PMID: 23394117
Do you know of a great paper that uses Virodhamine trifluoroacetate from Tocris? Please let us know.
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