Virodhamine trifluoroacetate
Biological Activity
TFA salt of virodhamine, an endogenous cannabinoid receptor mixed agonist/antagonist that is found in higher concentrations peripherally than anandamide. Virodhamine is a full agonist at GPR55 and CB2 and partial agonist/antagonist at CB1 (EC50 values are 12, 381 and 2920 nM at GPR55, CB2 and CB1 receptors respectively).
Technical Data
| M. Wt | 461.56 |
| Formula | C22H37NO2.CF3CO2H |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 1415264-56-0 |
| PubChem ID | 91691131 |
| InChI Key | APQWCQIPZHJFAU-XVSDJDOKSA-N |
| Smiles | O=C(OCCN)CCC\C=C/C\C=C/C/C=C\C/C=C\CCCCC.FC(F)(F)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 461.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.17 mL | 10.83 mL | 21.67 mL |
| 5 mM | 0.43 mL | 2.17 mL | 4.33 mL |
| 10 mM | 0.22 mL | 1.08 mL | 2.17 mL |
| 50 mM | 0.04 mL | 0.22 mL | 0.43 mL |
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References
References are publications that support the products' biological activity.
Porter et al (2002) Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor. J.Pharmacol.Exp.Ther. 301 1020 PMID: 12023533
If you know of a relevant reference for Virodhamine trifluoroacetate, please let us know.
View Related Products by Target
Keywords: Virodhamine TFA GPR55 CB2 agonists CB1 partial antagonists non-selective cannabinoids receptors cb2r cb1r Trifluoroacetic acid salt Non-selective Cannabinoids
Citations for Virodhamine trifluoroacetate
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