Travaprost

Discontinued Product

Travaprost (Cat. No. 4218) has been withdrawn from sale for commercial reasons.
Description: Potent and selective FP prostaglandin receptor agonist
Chemical Name: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic acid 1-methyethyl ester
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews

Biological Activity for Travaprost

Travaprost is a FP prostaglandin receptor agonist. Exhibits submicromolar affinity for DP, EP, IP and TP receptors. Stimulates intracellular Ca2+ mobilization. Ocular hypotensive agent.

Technical Data for Travaprost

M. Wt 500.55
Formula C26H35F3O6
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 157283-68-6
PubChem ID 5282226
InChI Key MKPLKVHSHYCHOC-AHTXBMBWSA-N
Smiles O[C@@H]1[C@H](C/C=C\CCCC(OC(C)C)=O)[C@@H](/C=C/[C@@H](O)COC2=CC=CC(C(F)(F)F)=C2)[C@H](O)C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Travaprost

Certificate of Analysis / Product Datasheet
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References for Travaprost

References are publications that support the biological activity of the product.

Hellberg et al (2001) Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist. J.Ocul.Pharmacol.Ther. 17 421 PMID: 11765147

Sharif et al (1999) [3H]AL-5848 ([3H]9beta-(+)-Fluprostenol). Carboxylic acid of travo. (AL-6221), a novel FP prostaglandin to study the pharmacology and autoradiographic localization of the FP receptor. J.Pharm.Pharmacol. 51 685 PMID: 10454045

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Keywords: Travaprost, Travaprost supplier, Supplier, Travoprost, FP, receptor, agonist, prostaglandin, F2a, F2alpha, ocular, hypotensive, Prostanoid, Receptors, 4218, Tocris Bioscience

Citations for Travaprost

Citations are publications that use Tocris products.

Currently there are no citations for Travaprost.

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