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Very potent and selective NMDA agonist. Certain confusion exists over the naming of this compound because of apparent contradictions in the literature. This is the isomer which has the carboyxlic acid and the amino groups on opposite sides of the cyclobutyl ring. cis-ACBD (Cat. No. 0271) also available.
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The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Allan et al (1990) Synthesis and activity of a potent NMDA agonist, trans-1-aminocyclobutane-1,3-dicarboxylic acid, and related phosphonic and carboxylic acids. J.Med.Chem. 33 2905 PMID: 2145435
Lanthorn et al (1990) cis-2,4-Methanoglutamate is a potent and selective NMDA receptor agonist. Eur.J.Pharmacol. 182 397 PMID: 2146136
Keywords: trans-ACBD, trans-ACBD supplier, Selective, potent, NMDA, agonists, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, 0270, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
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