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Discontinued Product
trans-ACBD (Cat. No. 0270) has been withdrawn from sale for commercial reasons.
Description: Selective, very potent NMDA agonist
Chemical Name: trans-1-Aminocyclobutane-1,3-dicarboxylic acid
Biological Activity for trans-ACBD
Very potent and selective NMDA agonist. Certain confusion exists over the naming of this compound because of apparent contradictions in the literature. This is the isomer which has the carboyxlic acid and the amino groups on opposite sides of the cyclobutyl ring. cis-ACBD (Cat. No. 0271) also available.
Technical Data for trans-ACBD
| M. Wt | 159.14 |
| Formula | C6H9NO4 |
| Storage | Store at RT |
| CAS Number | 117488-23-0 |
| Smiles | [H][C@]1([C@](O)=O)C[C@@](N)([C@](O)=O)C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for trans-ACBD
References for trans-ACBD
References are publications that support the biological activity of the product.
Allan et al (1990) Synthesis and activity of a potent NMDA agonist, trans-1-aminocyclobutane-1,3-dicarboxylic acid, and related phosphonic and carboxylic acids. J.Med.Chem. 33 2905 PMID: 2145435
Lanthorn et al (1990) cis-2,4-Methanoglutamate is a potent and selective NMDA receptor agonist. Eur.J.Pharmacol. 182 397 PMID: 2146136
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Keywords: trans-ACBD, trans-ACBD supplier, Selective, potent, NMDA, agonists, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, 0270, Tocris Bioscience
Citations for trans-ACBD
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Currently there are no citations for trans-ACBD.
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