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Tocriscreen Library of FDA-Approved Compounds
A library of 159 FDA-approved compounds supplied pre-dissolved in DMSO (250 μL 10 mM solution). Contains compounds covering a range of therapeutic classes e.g. the cardiovascular and nervous systems and research areas such as cancer and immunology. Includes both established gold-standard compounds, e.g. tamoxifen, paclitaxel, as well as more recent highly selective, targeted compounds, such as gefitinib and axitinib.
Key Format and Product Details
- All compounds are FDA-approved
- Full chemical and biological data available
- 96-well racks with Matrix storage tubes & SepraSeal caps
- Compounds arranged 80 per rack with 2 racks per library
- Pre-dissolved in 250 μL 10 mM DMSO solutions
- Compounds produced to same high chemical standard as Tocris catalog
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Li et al (2015) Small-molecule-driven direct reprogramming of mouse fibroblasts into functional neurons. Cell Stem Cell 17 195 PMID: 26253201
Yu et al (2015) Small molecules enhance CRISPR genome editing in pluripotent stem cells. Cell Stem Cell 16 142 PMID: 25658371
Edwards et al (2014) The University of New Mexico Center for Molecular Discovery. Comb.Chem.High Throughput Screen. 17 256 PMID: 24409953
Li et al (2011) Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules. Cell Research 21 196 PMID: 20956998
Beacham et al (2010) Cell-based potassium ion channel screening using the FluxORTM assay. J.Biomol.Screen. 15 44 PMID: 20208034.
Hattori et al (2010) Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis. Proc.Natl.Acad.Sci.USA 107 3546 PMID: 20142487
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