Tocriscreen Library of FDA-Approved Compounds

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Cat.No. 5932 - Tocriscreen Library of FDA-Approved Compounds | xx
Description: A library of 160 FDA-approved compounds (250 μL 10 mM DMSO solutions)
Datasheet
Citations
Literature

Biological Activity

A library of 160 FDA-approved compounds. Comprises a subset of the Tocriscreen Plus (Cat. No. 5840) compound library. Contains compounds covering a range of therapeutic classes e.g. the cardiovascular and nervous systems and research areas such as cancer and immunology. Includes both established gold-standard compounds, e.g. tamoxifen, paclitaxel, as well as more recent highly selective, targeted compounds, such as gefitinib and axitinib.

Key Format and Product Details

  • All compounds are FDA-approved
  • Full chemical and biological data available
  • 96-well racks with Matrix storage tubes & SepraSeal caps
  • Compounds arranged 80 per rack with 2 racks per library
  • Pre-dissolved in 250 μL 10 mM DMSO solutions
  • Compounds produced to same high chemical standard as Tocris catalog

Request Compound List

To request a list of the compounds available in the Tocriscreen Library of FDA-Approved Compounds please click the request tile below. Compound lists can be provided in Excel or SD format.

Request compound list for Tocriscreen Library of FDA-Approved Compounds

Technical Data

Storage Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service.
Safety Datasheet

References

References are publications that support the products' biological activity.

Li et al (2015) Small-molecule-driven direct reprogramming of mouse fibroblasts into functional neurons. Cell Stem Cell 17 195 PMID: 26253201

Yu et al (2015) Small molecules enhance CRISPR genome editing in pluripotent stem cells. Cell Stem Cell 16 142 PMID: 25658371

Edwards et al (2014) The University of New Mexico Center for Molecular Discovery. Comb.Chem.High Throughput Screen. 17 256 PMID: 24409953

Li et al (2011) Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules. Cell Research 21 196 PMID: 20956998

Beacham et al (2010) Cell-based potassium ion channel screening using the FluxORTM assay. J.Biomol.Screen. 15 44 PMID: 20208034.

Hattori et al (2010) Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis. Proc.Natl.Acad.Sci.USA 107 3546 PMID: 20142487


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Citations for Tocriscreen Library of FDA-Approved Compounds

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New Product Guide

New Product Guide (Spring/Summer 2017)

Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Apoptosis
  • Cell Metabolism
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells

Pathways for Tocriscreen Library of FDA-Approved Compounds

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