Tocriscreen Epigenetics Toolbox

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Cat.No. 5268 - Tocriscreen Epigenetics Toolbox
Description: 80 Epigenetic modulators supplied pre-dissolved in DMSO (250 μL 10 mM solutions)
Datasheet
Citations (1)
Reviews
Literature

Biological Activity

A collection of 80 chemical modulators for Epigenetics Research supplied as pre-dissolved DMSO solutions (250 μl 10 mM solution per compound).

Key Format and Product Details

  • 96-well rack with Matrix storage tubes & SepraSeal caps
  • Pre-dissolved in DMSO
  • All compounds are biologically active
  • Many compounds are exclusive to Tocris
  • Full chemical and biological data available
  • Exceptional purity

Request Compound List

To request a list of the compounds available in the Tocriscreen Epigenetics Toolbox please click the request tile below. Compound lists can be provided in Excel or SD format.

Request compound list for Tocriscreen Epigenetics Toolbox

Technical Data

Storage Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service.
Safety Datasheet

References

References are publications that support the products' biological activity.

If you know of a relevant reference for Tocriscreen Epigenetics Toolbox, please let us know.

Keywords: Tocriscreen Epigenetics Toolbox, supplier, Tocriscreens, Epigenetics, Toolbox, compounds, libraries, library, screening, tools, histones, readers, writers, erasers, bromodomains, BET, BRD, DNA, methyltransferases, HMTs, MBT, L3MBT, RNA, polymerases, demethylases, HDMs, acetyltransferases, HATs, deacetylases, HDACS, KDMs, modu, Tocriscreen, Toolboxes, Tocriscreen, Toolboxes, Tocris Bioscience

1 Citation for Tocriscreen Epigenetics Toolbox

Citations are publications that use Tocris products. Selected citations for Tocriscreen Epigenetics Toolbox include:

Andricovich (2018) Loss of KDM6A activates super-enhancers to induce gender-specific squamous-like pancreatic cancer and confers sensitivity to BET inhibitors. Cancer Cell 33 512 PMID: 29533787


Do you know of a great paper that uses Tocriscreen Epigenetics Toolbox from Tocris? If so please let us know.

Reviews for Tocriscreen Epigenetics Toolbox

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Epigenetics

Epigenetics Scientific Review

Written by Susanne Müller-Knapp and Peter J. Brown, this review gives an overview of the development of chemical probes for epigenetic targets, as well as the impact of these tool compounds being made available to the scientific community. In addition, their biological effects are also discussed. Epigenetic compounds available from Tocris are listed.

MAPK Signaling

MAPK Signaling Scientific Review

MAP kinase signaling is integral to the regulation of numerous cellular processes such as proliferation and differentiation, and as a result is an important focus of cancer and immunology research. Updated for 2016, this review discusses the regulation of the MAPK pathway and properties of MAPK cascades. Compounds available from Tocris are listed.

Stem Cells

Stem Cells Scientific Review

Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.

Stem Cells

Stem Cells Poster

Written by Rebecca Quelch and Stefan Przyborski from Durham University (UK), this poster describes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and the generation and potential uses of organoids.