An effective non-competitive NMDA receptor antagonist in vivo and in vitro; may bind to more than one site, one of which is the polyamine site.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 5 mM in water|
Preparing Stock Solutions
The following data is based on the product molecular weight 354.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.82 mL||14.11 mL||28.21 mL|
|5 mM||0.56 mL||2.82 mL||5.64 mL|
|10 mM||0.28 mL||1.41 mL||2.82 mL|
|50 mM||0.06 mL||0.28 mL||0.56 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Reynolds et al (1991) 1,10-Bis(guanidino)decane inhibits N-methyl-D-aspartate responses in vitro and in vivo. J.Pharmacol.Exp.Ther. 259 626 PMID: 1658306
Reynolds (1992) Interactions between zinc and spermidine on the N-methyl-D-aspartate receptor complex: clues to the mechanism of action of 1,10-bis(guanidino)decane and pentamidine. J.Pharmacol.Exp.Ther. 263 632 PMID: 1432693
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Keywords: Non-competitive NMDA antagonists Glutamate Receptors N-Methyl-D-Aspartate iGluR Ionotropic NMDA Receptors
Citations for Synthalin sulfate
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