Vasoconstrictor peptide; non-selective endothelin receptor agonist.
(Modifications: Disulfide bridge between: 1-15, 3-11)
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 1 mg/ml in 20% acetonitrile|
Preparing Stock Solutions
The following data is based on the product molecular weight 2564. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||0.39 mL||1.95 mL||3.9 mL|
|5 mM||0.08 mL||0.39 mL||0.78 mL|
|10 mM||0.04 mL||0.2 mL||0.39 mL|
|50 mM||0.01 mL||0.04 mL||0.08 mL|
References are publications that support the biological activity of the product.
Aimoto et al (1990) Studies on the disulfide bridges of sarafotoxins. Chemical synthesis of sarafotoxin S6B and its homologue with different disulfide bridges. Biochem.Int. 21 1051 PMID: 2080919
Bax et al (1994) Different endothelin receptors involved in endothelin-1- and sarafotoxin S6B-induced contractions of the human isolated coronary artery. Br.J.Pharmacol. 113 1471 PMID: 7889304
Devadason and Henry (1997) Comparison of the contractile effects and binding kinetics of endothelin-1 and sarafotoxin S6b in rat isolated renal artery. Br.J.Pharmacol. 121 253 PMID: 9154335
If you know of a relevant reference for Sarafotoxin S6b, please let us know.
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Keywords: Sarafotoxin S6b, Sarafotoxin S6b supplier, Endothelin, receptor, agonists, non-selective, Non-Selective, ET, Receptors, ETA, ETB, SarafotoxinS6b, Non-selective, 1174, Tocris Bioscience
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