Home / Pharmacology / GPCRs / 7-TM Receptors / Peptide Receptors / Endothelin Receptors / Non-selective Endothelin / Non-selective Endothelin Agonists / Sarafotoxin S6a

Sarafotoxin S6a

Cat. No. 1899 Submit a Review Datasheet / COA / SDS

Discontinued Product

1899 has been discontinued.

View all Non-selective Endothelin products.
Description: Endothelin receptor agonist
Datasheet
Citations
Reviews
Biological Activity Technical Data Datasheets References

Biological Activity for Sarafotoxin S6a

Endothelin receptor agonist (EC50 values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo.

Technical Data for Sarafotoxin S6a

M. Wt 2514.85
Formula C105H156N28O34S5
Sequence CSCKDMTDKECLNFCHQDVIW

(Modifications: Disulfide bridge between 1 - 15, 3 - 11)
Storage Desiccate at -20°C
CAS Number 126738-34-9
PubChem ID 71308664
InChI Key BOQKWORWRAYXSI-SQCNKGOOSA-N
Smiles [H]N[C@H]1CSSC[C@H](NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N2)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Sarafotoxin S6a

Certificate of Analysis / Product Datasheet
Select another batch:
Safety Datasheet

References for Sarafotoxin S6a

References are publications that support the biological activity of the product.

Minkes et al (1992) Comparison of responses to sarafotoxins 6a and 6c in pulmonary and systemic vascular beds. Am.J.Physiol. 262 H852 PMID: 1348398

Raffa et al (1996) Endothelin-induced nociception in mice: mediation by ETA and ETB receptors. J.Pharmacol.Exp.Ther. 276 647 PMID: 8632332

Schoeffter and Randriantsoa (1993) Differences between endothelial receptors mediating contraction of guinea-pig aorta and pig coronary artery. Eur.J.Pharmacol. 249 199 PMID: 8287901

View Related Products by Target

View Related Products by Product Action

View all Non-selective Endothelin Agonists

Keywords: Sarafotoxin S6a, Sarafotoxin S6a supplier, Endothelin, receptor, agonists, Non-Selective, ET, Receptors, SarafotoxinS6a, Non-selective, 1899, Tocris Bioscience

Citations for Sarafotoxin S6a

Citations are publications that use Tocris products.

Currently there are no citations for Sarafotoxin S6a.

Reviews for Sarafotoxin S6a

There are currently no reviews for this product. Be the first to review Sarafotoxin S6a and earn rewards!

Have you used Sarafotoxin S6a?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review