S 107 hydrochloride
Discontinued ProductUnfortunately S 107 hydrochloride (Cat. No. 3893) has been withdrawn from sale for commercial reasons.
Type 1 ryanodine receptor (RyR1) stabilizer; binds RyR1 and enhances the binding affinity of calstabin-1. Inhibits Ca2+ leak from the sarcoplasmic reticulum (SR). Activity results in improved muscle function and increased exercise performance in a Duchenne muscular dystrophy (DMD) mouse model (mdx). Also reduces exercise-induced muscle damage by lowering calpain activation and plasma creatine kinase levels.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 245.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4.07 mL||20.34 mL||40.69 mL|
|5 mM||0.81 mL||4.07 mL||8.14 mL|
|10 mM||0.41 mL||2.03 mL||4.07 mL|
|50 mM||0.08 mL||0.41 mL||0.81 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Keywords: ryanodine receptors RyR1inhibits inhibitors calcium Ca2+ leak sarcoplasmic reticulum muscle function damage S107 General Calcium Signaling Agents
Citations for S 107 hydrochloride
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Currently there are no citations for S 107 hydrochloride.