Agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). Homolog of gonadotropin-inhibitory hormone (GnIH); inhibits activity of gonadotropin-releasing hormone (GnRH) neurons.
(Phe-8 = C-terminal amide)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 2 mg/ml in 20% acetonitrile / water|
Preparing Stock Solutions
The following data is based on the product molecular weight 969.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.03 mL||5.16 mL||10.32 mL|
|5 mM||0.21 mL||1.03 mL||2.06 mL|
|10 mM||0.1 mL||0.52 mL||1.03 mL|
|50 mM||0.02 mL||0.1 mL||0.21 mL|
References are publications that support the products' biological activity.
Rizwan et al (2012) RFamide-related peptide-3 receptor gene expression in GnRH and kisspeptin neurons and GnRH-dependent mechanism of action. Endocrinology 153 3770 PMID: 22691552
Ubuka et al (2009) Identification of human GnIH homologs, RFRP-1 and RFRP-3, and the cognate receptor, GPR147 in the human hypothalamic pituitary axis. PLoS One 4 e8400 PMID: 20027225
Hinuma et al (2000) New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals. Nat.Cell Biol. 2 703 PMID: 11025660
If you know of a relevant reference for RFRP 3 (human), please let us know.
View Related Products by Product Action
Keywords: RFRP 3 (human), supplier, RFamide-related, peptide, RFRP3, neuropeptide, FF/AF, agonists, gonadotropin-inhibitory, gonadotrophin-inhibitory, hormone, homologs, orthologs, GnIH, Neuropeptide, NPVF, Neuropeptide, NPVF, Neuropeptide, FF/AF, Receptors, Neuropeptide, FF/AF, Receptors, Tocris Bioscience
Citations for RFRP 3 (human)
Citations are publications that use Tocris products.
Currently there are no citations for RFRP 3 (human). Do you know of a great paper that uses RFRP 3 (human) from Tocris? If so please let us know.
Reviews for RFRP 3 (human)
There are currently no reviews for this product. Be the first to review RFRP 3 (human) and earn rewards!
Have you used RFRP 3 (human)?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.