PAR 4 (1-6)

Discontinued Product

Unfortunately PAR 4 (1-6) (Cat. No. 3494) has been withdrawn from sale for commercial reasons.
Cat.No. 3494 - PAR 4 (1-6) | Gly-Tyr-Pro-Gly-Gln-Val | CAS No. 225779-44-2
Description: PAR4 peptide fragment; acts as a PAR4 agonist

Biological Activity

N-terminal fragment of protease-activated receptor 4 (PAR4) that acts as a PAR4 agonist. Induces aggregation of human platelets.

Technical Data

M. Wt 619.68
Formula C28H41N7O9
Sequence GYPGQV
Storage Store at -20°C
CAS Number 225779-44-2
Smiles [H]NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 619.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.61 mL 8.07 mL 16.14 mL
5 mM 0.32 mL 1.61 mL 3.23 mL
10 mM 0.16 mL 0.81 mL 1.61 mL
50 mM 0.03 mL 0.16 mL 0.32 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet


References are publications that support the products' biological activity.

Xu et al (1998) Cloning and characterization of human protease-activated receptor 4. Proc.Natl.Acad.Sci.USA 95 6642 PMID: 9618465

Andersen et al (1999) Protease-activated receptor 1 is the primary mediator of thrombin-stimulated platelet procoagulant activity. Proc.Natl.Acad.Sci.U.S.A. 96 11189 PMID: 10500152

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Keywords: PAR 4 (1-6), supplier, PAR4, peptide, fragment, agonists, Receptors, Protease-Activated, proteinase-activated, (1-6), Protease-Activated, Receptors, Protease-Activated, Receptors, Tocris Bioscience

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