PAR 4 (1-6)

Discontinued Product

Unfortunately PAR 4 (1-6) (Cat. No. 3494) has been withdrawn from sale for commercial reasons.
Cat.No. 3494 - PAR 4 (1-6) | Gly-Tyr-Pro-Gly-Gln-Val | CAS No. 225779-44-2
Description: PAR4 peptide fragment; acts as a PAR4 agonist
Datasheet
Citations
Literature

Biological Activity

N-terminal fragment of protease-activated receptor 4 (PAR4) that acts as a PAR4 agonist. Induces aggregation of human platelets.

Technical Data

M. Wt 619.68
Formula C28H41N7O9
Sequence GYPGQV
Storage Store at -20°C
CAS Number 225779-44-2
Smiles [H]NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 619.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.61 mL 8.07 mL 16.14 mL
5 mM 0.32 mL 1.61 mL 3.23 mL
10 mM 0.16 mL 0.81 mL 1.61 mL
50 mM 0.03 mL 0.16 mL 0.32 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Xu et al (1998) Cloning and characterization of human protease-activated receptor 4. Proc.Natl.Acad.Sci.USA 95 6642 PMID: 9618465

Andersen et al (1999) Protease-activated receptor 1 is the primary mediator of thrombin-stimulated platelet procoagulant activity. Proc.Natl.Acad.Sci.U.S.A. 96 11189 PMID: 10500152

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Keywords: PAR 4 (1-6), supplier, PAR4, peptide, fragment, agonists, Receptors, Protease-Activated, proteinase-activated, (1-6), Protease-Activated, Receptors, Tocris Bioscience

Citations for PAR 4 (1-6)

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Currently there are no citations for PAR 4 (1-6).

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Literature in this Area

Cardiovascular

Cardiovascular Research Product Guide

A collection of over 250 products for cardiovascular research, the guide includes research tools for the study of:

  • Hypertension
  • Thrombosis and Hemostasis
  • Atherosclerosis
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  • Ischemia/Reperfusion Injury
  • Arrhythmias
  • Heart Failure
GPCR

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
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Cardiovascular

Cardiovascular Poster

Cardiovascular disease remains one of the major causes of morbidity and mortality in the Western world and therefore this therapeutic area continues to be of great interest to researchers. This poster highlights the key GPCRs regulating vascular reactivity.

Pathways for PAR 4 (1-6)

Protocols

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