Oxotremorine sesquifumarate

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Description: Muscarinic agonist
Chemical Name: 1-[4-(1-Pyrrolidinyl)-2-butynyl]-2-pyrrolidinone sesquifumarate
Purity: ≥98% (HPLC)
Citations (3)
Literature (1)

Biological Activity for Oxotremorine sesquifumarate

Oxotremorine sesquifumarate is a muscarinic agonist.

Technical Data for Oxotremorine sesquifumarate

M. Wt 380.4
Formula C12H18N2O.1.5C4H4O4
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 17360-35-9
PubChem ID 6436473

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Oxotremorine sesquifumarate

Solvent Max Conc. mg/mL Max Conc. mM
water 9.51 25
DMSO 38.04 100

Preparing Stock Solutions for Oxotremorine sesquifumarate

The following data is based on the product molecular weight 380.4. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.63 mL 13.14 mL 26.29 mL
5 mM 0.53 mL 2.63 mL 5.26 mL
10 mM 0.26 mL 1.31 mL 2.63 mL
50 mM 0.05 mL 0.26 mL 0.53 mL

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Product Datasheets for Oxotremorine sesquifumarate

Certificate of Analysis / Product Datasheet
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References for Oxotremorine sesquifumarate

References are publications that support the biological activity of the product.

Fisher et al (1984) Differential stimulation in inositol phospholipid turnover in brain by analogs of oxotremorine. J.Neurochem. 43 1171 PMID: 6088696

Moroi-Fetters et al (1988) Muscarinic receptor-mediated phosphoinositide hydrolysis in the rat retina. J.Pharmacol.Exp.Ther. 246 553 PMID: 2841451

Merck Index 12 7085

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Keywords: Oxotremorine sesquifumarate, Oxotremorine sesquifumarate supplier, Muscarinic, agonist, Receptors, Acetylcholine, ACh, Non-selective, Muscarinics, 0843, Tocris Bioscience

3 Citations for Oxotremorine sesquifumarate

Citations are publications that use Tocris products. Selected citations for Oxotremorine sesquifumarate include:

Bragança et al (2016) Ion Fluxes through KCa2 (SK) and Cav1 (L-type) Channels Contribute to Chronoselectivity of Adenosine A1 Receptor-Mediated Actions in Spontaneously Beating Rat Atria. Front Pharmacol 7 45 PMID: 27014060

Deng et al (2013) Label-free cell phenotypic assessment of the biased agonism and efficacy of agonists at the endogenous muscarinic M3 receptors. J Pharmacol Toxicol Methods 68 323 PMID: 23933114

Carneiro et al (2014) Activation of P2Y6 receptors increases the voiding frequency in anaesthetized rats by releasing ATP from the bladder urothelium. Br J Pharmacol 171 3404 PMID: 24697602

Do you know of a great paper that uses Oxotremorine sesquifumarate from Tocris? Please let us know.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

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