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High affinity, water-soluble CB1/CB2 receptor agonist (Ki values are 1.5 and 0.32 nM for CB1 and CB2 receptors respectively). Active in vivo following i.v. and i.c.v. administration.
Sold under license from VCU-IPF
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|water||8.9||20 with gentle warming|
Preparing Stock Solutions
The following data is based on the product molecular weight 445.04. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.25 mL||11.23 mL||22.47 mL|
|5 mM||0.45 mL||2.25 mL||4.49 mL|
|10 mM||0.22 mL||1.12 mL||2.25 mL|
|50 mM||0.04 mL||0.22 mL||0.45 mL|
References are publications that support the biological activity of the product.
Martin et al (2006) Pharmacological characterization of novel water-soluble cannabinoids. J.Pharmacol.Exp.Ther. 318 1230 PMID: 16757541
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Keywords: O-2545 hydrochloride, O-2545 hydrochloride supplier, High, affinity, water-soluble, CB1/CB2, agonists, Non-Selective, cannabinoids, Receptors, cb2r, cb1r, Non-selective, Cannabinoids, 2680, Tocris Bioscience
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