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Submit ReviewO-2545 hydrochloride
Discontinued Product
O-2545 hydrochloride (Cat. No. 2680) has been withdrawn from sale for commercial reasons.
Description: High affinity, water-soluble CB1/CB2 agonist
Chemical Name: (6aR,10aR)-6a,7,10,10a-Tetrahydro-3-[5-(1H-imidazol-1-yl)-1,1-dimethylpentyl]-6,6,9-trimethyl-6H-dibenzo[b,d]pyran-1-ol hydrochloride
Purity: ≥99% (HPLC)
Biological Activity for O-2545 hydrochloride
O-2545 hydrochloride is a high affinity, water-soluble CB1/CB2 receptor agonist (Ki values are 1.5 and 0.32 nM for CB1 and CB2 receptors respectively). Active in vivo following i.v. and i.c.v. administration.
Licensing Information
Sold under license from VCU-IPF
Technical Data for O-2545 hydrochloride
| M. Wt | 445.04 |
| Formula | C26H36N2O2.HCl |
| Storage | Store at -20°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 874745-43-4 |
| PubChem ID | 24848973 |
| InChI Key | LSHUCXYFAOTXLT-MUCZFFFMSA-N |
| Smiles | OC1=CC(C(C)(C)CCCCN4C=CN=C4)=CC3=[C@@]1[C@H]2[C@H]([C@@](C)(C)O3)CC=C(C)C2.Cl |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for O-2545 hydrochloride
References for O-2545 hydrochloride
References are publications that support the biological activity of the product.
Martin et al (2006) Pharmacological characterization of novel water-soluble cannabinoids. J.Pharmacol.Exp.Ther. 318 1230 PMID: 16757541
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Keywords: O-2545 hydrochloride, O-2545 hydrochloride supplier, High, affinity, water-soluble, CB1/CB2, agonists, Non-Selective, cannabinoids, Receptors, cb2r, cb1r, Non-selective, Cannabinoids, 2680, Tocris Bioscience
Citations for O-2545 hydrochloride
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Currently there are no citations for O-2545 hydrochloride.
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