O-2545 hydrochloride

Discontinued Product

O-2545 hydrochloride (Cat. No. 2680) has been withdrawn from sale for commercial reasons.
Description: High affinity, water-soluble CB1/CB2 agonist
Chemical Name: (6aR,10aR)-6a,7,10,10a-Tetrahydro-3-[5-(1H-imidazol-1-yl)-1,1-dimethylpentyl]-6,6,9-trimethyl-6H-dibenzo[b,d]pyran-1-ol hydrochloride
Purity: ≥99% (HPLC)
Literature (1)

Biological Activity for O-2545 hydrochloride

O-2545 hydrochloride is a high affinity, water-soluble CB1/CB2 receptor agonist (Ki values are 1.5 and 0.32 nM for CB1 and CB2 receptors respectively). Active in vivo following i.v. and i.c.v. administration.

Licensing Information

Sold under license from VCU-IPF

Technical Data for O-2545 hydrochloride

M. Wt 445.04
Formula C26H36N2O2.HCl
Storage Store at -20°C
Purity ≥99% (HPLC)
CAS Number 874745-43-4
PubChem ID 24848973
Smiles OC1=CC(C(C)(C)CCCCN4C=CN=C4)=CC3=[C@@]1[C@H]2[C@H]([C@@](C)(C)O3)CC=C(C)C2.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for O-2545 hydrochloride

References for O-2545 hydrochloride

References are publications that support the biological activity of the product.

Martin et al (2006) Pharmacological characterization of novel water-soluble cannabinoids. J.Pharmacol.Exp.Ther. 318 1230 PMID: 16757541

View Related Products by Target

View Related Products by Product Action

View all Non-selective Cannabinoid Agonists

Keywords: O-2545 hydrochloride, O-2545 hydrochloride supplier, High, affinity, water-soluble, CB1/CB2, agonists, Non-Selective, cannabinoids, Receptors, cb2r, cb1r, Non-selective, Cannabinoids, 2680, Tocris Bioscience

Citations for O-2545 hydrochloride

Citations are publications that use Tocris products.

Currently there are no citations for O-2545 hydrochloride.

Reviews for O-2545 hydrochloride

There are currently no reviews for this product. Be the first to review O-2545 hydrochloride and earn rewards!

Have you used O-2545 hydrochloride?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Cannabinoid Receptor Ligands Scientific Review

Cannabinoid Receptor Ligands Scientific Review

Written by Roger Pertwee, this review discusses compounds which affect the activity of the endocannabinoid system, focusing particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.