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Anti-inflammatory agent; increases intracellular Ca2+ levels.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|DMSO||35.34||100 with gentle warming|
Preparing Stock Solutions
The following data is based on the product molecular weight 353.42. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.83 mL||14.15 mL||28.29 mL|
|5 mM||0.57 mL||2.83 mL||5.66 mL|
|10 mM||0.28 mL||1.41 mL||2.83 mL|
|50 mM||0.06 mL||0.28 mL||0.57 mL|
References are publications that support the biological activity of the product.
Burch et al (1991) N-(Fluorenyl-9-methoxycarbonyl) amino acids, a class of anti-inflammatory agents with a different mechanism of action. Proc.Natl.Acad.Sci.U.S.A. 88 355 PMID: 1824872
Jan et al (2000) NPC-15199, a novel anti-inflammatory agent, mobilizes intracellular Ca2+ in bladder female transitional carcinoma (BFTC) cells. Chin.J.Physiol. 43 29 PMID: 10857466
Miller et al (1993) Guinea pig ileitis is attenuated by the leumidin N-(fluorenyl-9-methoxycarbonyl)leucine (NPC 15199). J.Pharmacol.Exp.Ther. 266 468 PMID: 8392562
If you know of a relevant reference for NPC 15199, please let us know.
Keywords: NPC 15199, NPC 15199 supplier, Increases, intracellular, Ca2+, levels, Calcium, Signaling, Signalling, Agents, General, anti-inflammatory, NPC15199, 0675, Tocris Bioscience
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