Neuropeptide SF (human)

Discontinued Product

Unfortunately Neuropeptide SF (human) (Cat. No. 1886) has been withdrawn from sale for commercial reasons.
Cat.No. 1886 - Neuropeptide SF (human) | Ser-Gln-Ala-Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2 | CAS No. 192387-39-6
Description: Implicated in pain modulation and opioid function
Alternative Names: Neuropeptide NPFF (human FMRFamide-related)
Datasheet
Citations
Literature

Biological Activity

Endogenous antiopioid peptide, implicated in pain modulation and endocrine functions. Potently activates the orphan G-protein-coupled receptor HLWAR77 (NPFF2) (EC50 = 0.39 nM).

Technical Data

M. Wt 1367.57
Formula C65H94N18O15
Sequence SQAFLFQPQRF

(Modifications: Phe-11 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 192387-39-6
Smiles [H]N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 1367.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.73 mL 3.66 mL 7.31 mL
5 mM 0.15 mL 0.73 mL 1.46 mL
10 mM 0.07 mL 0.37 mL 0.73 mL
50 mM 0.01 mL 0.07 mL 0.15 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Elshourbagy et al (2000) Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor. J.Biol.Chem. 275 25965 PMID: 10851242

Keywords: Neuropeptide SF (human), supplier, Implicated, pain, modulation, Anti-opioids, NPFF, Receptors, Neuropeptides, FF/AF, HLWAR77, NPFFR2, NeuropeptideSF, (human), npff2, neuropeptide, Neuropeptide, NPFF, (human, FMRFamide-related), Miscellaneous/Non-selective, Opioids, Neuropeptide, FF/AF, Receptors, Neuropeptide, FF/AF, Receptors, Tocris Bioscience

Citations for Neuropeptide SF (human)

Citations are publications that use Tocris products.

Currently there are no citations for Neuropeptide SF (human).

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