Neuropeptide S (human)

Pricing Availability Delivery Time Qty
Cat.No. 2587 - Neuropeptide S (human) | Ser-Phe-Arg-Asn-Gly-Val-Gly-Thr-Gly-Met-Lys-Lys-Thr-Ser-Phe-Gln-Arg-Ala-Lys-Ser | CAS No. 412938-67-1
Description: Potent endogenous neuropeptide S receptor agonist
Datasheet
Citations
Literature

Biological Activity

Potent endogenous neuropeptide S receptor agonist (EC50 = 9.4 nM). Increases locomotor activity and wakefulness in mice. Also reduces anxiety-like behavior in mice.

Technical Data

M. Wt 2187.5
Formula C93H155N31O28S
Sequence SFRNGVGTGMKKTSFQRAKS
Storage Store at -20°C
CAS Number 412938-67-1
PubChem ID 44123843
InChI Key ZRCUKBVXFDZBKP-XJEBPGRNSA-N
Smiles [H]N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 1 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 2187.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.46 mL 2.29 mL 4.57 mL
5 mM 0.09 mL 0.46 mL 0.91 mL
10 mM 0.05 mL 0.23 mL 0.46 mL
50 mM 0.01 mL 0.05 mL 0.09 mL

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Reconstitution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Xu et al (2004) Neuropeptide S: a neuropeptide promoting arousal and anxiolytic-like effects. Neuron 43 487 PMID: 15312648


If you know of a relevant reference for Neuropeptide S (human), please let us know.

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Keywords: Neuropeptide S (human), supplier, potent, endogenous, neuropeptides, receptor, agonists, anxiety, sleep, Other, Peptide, Receptors, Other, Peptide, Receptors, Tocris Bioscience

Citations for Neuropeptide S (human)

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