NB-caged Tyrosine hydrochloride

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Cat.No. 6121 - NB-caged Tyrosine hydrochloride | C16H16N2O5.HCl | CAS No. 207727-86-4
Description: ortho-nitrobenzyl caged L- tyrosine
Chemical Name: O-[(2-Nitrophenyl)methyl]-L-tyrosine hydrochloride
Purity: ≥97% (HPLC)

Biological Activity

L-Tyrosine caged with photosensitive ortho-nitrobenzyl side chain. Rapidly releases tyrosine when photolyzed (300-350 nm excitation). Is readily incorporated into E.coli proteins via inclusion in growth media.

Technical Data

M. Wt 352.77
Formula C16H16N2O5.HCl
Storage Store at -20°C
Purity ≥97% (HPLC)
CAS Number 207727-86-4
PubChem ID 53393436
Smiles N[C@H](C(O)=O)CC1=CC=C(C=C1)OCC2=C([N+]([O-])=O)C=CC=C2.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 35.28 100

Preparing Stock Solutions

The following data is based on the product molecular weight 352.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.83 mL 14.17 mL 28.35 mL
5 mM 0.57 mL 2.83 mL 5.67 mL
10 mM 0.28 mL 1.42 mL 2.83 mL
50 mM 0.06 mL 0.28 mL 0.57 mL

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Product Datasheets

Safety Datasheet


References are publications that support the products' biological activity.

Miller et al (1998) Flash decaging of tyrosine sidechains in an ion channel. Neuron. 20 619 PMID: 9581754

Monk et al (2017) Rapid and inexpensive evaluation of nonstandard amino acid incorporation in Escherichia coli. ACS.Synth.Biol. 6 45 PMID: 27648665

If you know of a relevant reference for NB-caged Tyrosine hydrochloride, please let us know.

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