NB-caged Tyrosine hydrochloride

Discontinued Product

NB-caged Tyrosine hydrochloride (Cat. No. 6121) has been withdrawn from sale for commercial reasons.
Description: ortho-nitrobenzyl caged L- tyrosine
Alternative Names: ONBY
Chemical Name: O-[(2-Nitrophenyl)methyl]-L-tyrosine hydrochloride
Purity: ≥97% (HPLC)

Biological Activity for NB-caged Tyrosine hydrochloride

NB-caged Tyrosine hydrochloride is a L-Tyrosine caged with photosensitive ortho-nitrobenzyl side chain. Rapidly releases tyrosine when photolyzed (300-350 nm excitation). Is readily incorporated into E.coli proteins via inclusion in growth media.

Technical Data for NB-caged Tyrosine hydrochloride

M. Wt 352.77
Formula C16H16N2O5.HCl
Storage Store at -20°C
Purity ≥97% (HPLC)
CAS Number 207727-86-4
PubChem ID 53393436
Smiles N[C@H](C(O)=O)CC1=CC=C(C=C1)OCC2=C([N+]([O-])=O)C=CC=C2.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for NB-caged Tyrosine hydrochloride

References for NB-caged Tyrosine hydrochloride

References are publications that support the biological activity of the product.

Miller et al (1998) Flash decaging of tyrosine sidechains in an ion channel. Neuron. 20 619 PMID: 9581754

Monk et al (2017) Rapid and inexpensive evaluation of nonstandard amino acid incorporation in Escherichia coli. ACS.Synth.Biol. 6 45 PMID: 27648665

Wang et al (2019) Time-resolved protein activation by proximal decaging in living systems. Nature 569 509 PMID: 31068699

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Citations for NB-caged Tyrosine hydrochloride

Citations are publications that use Tocris products.

Currently there are no citations for NB-caged Tyrosine hydrochloride.

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