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Description: Lysosomal system c L-arginine uptake inhibitor
Chemical Name: N2-Methyl-L-arginine

Biological Activity for N2-Methyl-L-arginine

N2-Methyl-L-arginine is a selective L-arginine uptake inhibitor (Ki = 500 μM). Inhibits uptake of arginine by the lysosomal system c in human fibroblast in vitro.

Technical Data for N2-Methyl-L-arginine

M. Wt 188.23
Formula C7H16N4O2
Storage Store at RT
CAS Number 2480-28-6
PubChem ID 73046
Smiles NC(NCCC[C@H](NC)C(O)=O)=N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for N2-Methyl-L-arginine

Solvent Max Conc. mg/mL Max Conc. mM
water 18.82 100

Preparing Stock Solutions for N2-Methyl-L-arginine

The following data is based on the product molecular weight 188.23. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.31 mL 26.56 mL 53.13 mL
5 mM 1.06 mL 5.31 mL 10.63 mL
10 mM 0.53 mL 2.66 mL 5.31 mL
50 mM 0.11 mL 0.53 mL 1.06 mL

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Product Datasheets for N2-Methyl-L-arginine

References for N2-Methyl-L-arginine

References are publications that support the biological activity of the product.

Pisoni et al (1987) Important differences in cationic amino acid transport by lysosomal system c and system y+ of the human fibroblast. J.Biol.Chem. 262 15011 PMID: 3499437

If you know of a relevant reference for N2-Methyl-L-arginine, please let us know.

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Keywords: N2-Methyl-L-arginine, N2-Methyl-L-arginine supplier, Lysosomal, system, c, L-arginine, reuptake, inhibitors, inhibits, Ion, Pumps, Transporters, Other, Pumps/Transporters, 3513, Tocris Bioscience

Citations for N2-Methyl-L-arginine

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