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Cat.No. 3513 - N2-Methyl-L-arginine | C7H16N4O2 | CAS No. 2480-28-6
Description: Lysosomal system c L-arginine uptake inhibitor
Chemical Name: N2-Methyl-L-arginine

Biological Activity

Selective L-arginine uptake inhibitor (Ki = 500 μM). Inhibits uptake of arginine by the lysosomal system c in human fibroblast in vitro.

Technical Data

M. Wt 188.23
Formula C7H16N4O2
Storage Store at RT
CAS Number 2480-28-6
PubChem ID 73046
Smiles NC(NCCC[C@H](NC)C(O)=O)=N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
water 18.82 100

Preparing Stock Solutions

The following data is based on the product molecular weight 188.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.31 mL 26.56 mL 53.13 mL
5 mM 1.06 mL 5.31 mL 10.63 mL
10 mM 0.53 mL 2.66 mL 5.31 mL
50 mM 0.11 mL 0.53 mL 1.06 mL

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Product Datasheets

Safety Datasheet


References are publications that support the products' biological activity.

Pisoni et al (1987) Important differences in cationic amino acid transport by lysosomal system c and system y+ of the human fibroblast. J.Biol.Chem. 262 15011 PMID: 3499437

If you know of a relevant reference for N2-Methyl-L-arginine, please let us know.

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Keywords: Lysosomal system c L-arginine reuptake inhibitors inhibits Ion Pumps Transporters Other Ion Pumps/Transporters

Citations for N2-Methyl-L-arginine

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New Product Guide (Spring/Summer 2017)

Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.

  • 7-TM Receptors
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  • Transporters
  • Apoptosis
  • Cell Metabolism
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells

Pathways for N2-Methyl-L-arginine


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