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N2-Methyl-L-arginine is a selective L-arginine uptake inhibitor (Ki = 500 μM). Inhibits uptake of arginine by the lysosomal system c in human fibroblast in vitro.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
The following data is based on the product molecular weight 188.23. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||5.31 mL||26.56 mL||53.13 mL|
|5 mM||1.06 mL||5.31 mL||10.63 mL|
|10 mM||0.53 mL||2.66 mL||5.31 mL|
|50 mM||0.11 mL||0.53 mL||1.06 mL|
References are publications that support the biological activity of the product.
Pisoni et al (1987) Important differences in cationic amino acid transport by lysosomal system c and system y+ of the human fibroblast. J.Biol.Chem. 262 15011 PMID: 3499437
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Keywords: N2-Methyl-L-arginine, N2-Methyl-L-arginine supplier, Lysosomal, system, c, L-arginine, reuptake, inhibitors, inhibits, Ion, Pumps, Transporters, Other, Pumps/Transporters, 3513, Tocris Bioscience
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