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A mixed antagonist / partial agonist at the polyamine-NMDA site.
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The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Romano et al (1991) Polyamines modulate the binding of [3H]MK-801 to the solubilized N-MthD.-aspartate receptor. J.Neurochem. 57 811 PMID: 1830614
Williams et al (1992) An antagonist/partial agonist at the polyamine recognition site of the N-MthD.-aspartate receptor that alters the properties of the glutamate recognition site. J.Pharmacol.Exp.Ther. 262 539 PMID: 1354252
Keywords: N-(3-Aminopropyl)-1,10-decanediamine trihydrochloride, N-(3-Aminopropyl)-1,10-decanediamine trihydrochloride supplier, NMDA, Receptors, 0354, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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This product guide provides a background to Huntington's disease research and lists around 100 products for the study of:
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Recognition memory enables us to make judgements about whether or not we have encountered a particular stimulus before. This poster outlines the cellular mechanisms underlying recognition memory and its links to long-term depression, as well as the use of pharmacological intervention to assess the role of neurotransmitters in recognition memory.
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Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.