Muramyl Dipeptide

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Cat.No. 6366 - Muramyl Dipeptide | C19H32N4O11 | CAS No. 53678-77-6
Description: Activates NOD2 receptors
Chemical Name: N-Acetylmuramoyl-L-alanyl-D-α-glutamine
Purity: ≥98% (HPLC)
Literature (4)

Biological Activity

Bacterial peptidoglycan fragment that activates NOD2 receptors. Induces polarization of proinflammatory Ly6Chigh into Ly6Clow patrolling monocytes.

Technical Data

M. Wt 492.48
Formula C19H32N4O11
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 53678-77-6
PubChem ID 451714
Smiles C[C@@H](O[C@@H]1[C@@H](NC(C)=O)C(O)O[C@H](CO)[C@H]1O)C(N[C@@H](C)C(N[C@@H](C(N)=O)CCC(O)=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
water 49.25 100

Preparing Stock Solutions

The following data is based on the product molecular weight 492.48. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.03 mL 10.15 mL 20.31 mL
5 mM 0.41 mL 2.03 mL 4.06 mL
10 mM 0.2 mL 1.02 mL 2.03 mL
50 mM 0.04 mL 0.2 mL 0.41 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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References are publications that support the biological activity of the product.

Lessard et al (2017) Triggering of NOD2 receptor converts inflammatory Ly6Chigh into Ly6Clow monocytes with patrolling properties. Cell Rep. 20 1830 PMID: 28834747

If you know of a relevant reference for Muramyl Dipeptide, please let us know.

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Keywords: Muramyl Dipeptide, Muramyl Dipeptide supplier, NOD2, nod-like, receptors, activates, activators, bacterial, peptidoglycan, innate, immunity, pattern, recognition, Inflammasomes, 6366, Tocris Bioscience

Citations for Muramyl Dipeptide

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Literature in this Area

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