Muramyl Dipeptide

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Cat.No. 6366 - Muramyl Dipeptide | C19H32N4O11 | CAS No. 53678-77-6
Description: Activates NOD2 receptors
Chemical Name: N-Acetylmuramoyl-L-alanyl-D-α-glutamine
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Bacterial peptidoglycan fragment that activates NOD2 receptors. Induces polarization of proinflammatory Ly6Chigh into Ly6Clow patrolling monocytes.

Technical Data

M. Wt 492.48
Formula C19H32N4O11
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 53678-77-6
PubChem ID 451714
InChI Key BSOQXXWZTUDTEL-ZUYCGGNHSA-N
Smiles C[C@@H](O[C@@H]1[C@@H](NC(C)=O)C(O)O[C@H](CO)[C@H]1O)C(N[C@@H](C)C(N[C@@H](C(N)=O)CCC(O)=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 49.25 100

Preparing Stock Solutions

The following data is based on the product molecular weight 492.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.03 mL 10.15 mL 20.31 mL
5 mM 0.41 mL 2.03 mL 4.06 mL
10 mM 0.2 mL 1.02 mL 2.03 mL
50 mM 0.04 mL 0.2 mL 0.41 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Lessard et al (2017) Triggering of NOD2 receptor converts inflammatory Ly6Chigh into Ly6Clow monocytes with patrolling properties. Cell Rep. 20 1830 PMID: 28834747


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Keywords: Muramyl Dipeptide, supplier, NOD2, nod-like, receptors, activates, activators, bacterial, peptidoglycan, innate, immunity, pattern, recognition, Inflammasomes, Inflammasomes, Tocris Bioscience

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