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Muramyl Dipeptide

Cat. No. 6366 Submit a Review Datasheet / COA / SDS
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Cat.No. 6366 - Muramyl Dipeptide | C19H32N4O11 | CAS No. 53678-77-6
Description: Activates NOD2 receptors
Chemical Name: N-Acetylmuramoyl-L-alanyl-D-α-glutamine
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature (4)
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity for Muramyl Dipeptide

Muramyl Dipeptide is a bacterial peptidoglycan fragment that activates NOD2 receptors. Induces polarization of proinflammatory Ly6Chigh into Ly6Clow patrolling monocytes.

Technical Data for Muramyl Dipeptide

M. Wt 492.48
Formula C19H32N4O11
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 53678-77-6
PubChem ID 451714
InChI Key BSOQXXWZTUDTEL-ZUYCGGNHSA-N
Smiles C[C@@H](O[C@@H]1[C@@H](NC(C)=O)C(O)O[C@H](CO)[C@H]1O)C(N[C@@H](C)C(N[C@@H](C(N)=O)CCC(O)=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Muramyl Dipeptide

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 49.25 100

Preparing Stock Solutions for Muramyl Dipeptide

The following data is based on the product molecular weight 492.48. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.03 mL 10.15 mL 20.31 mL
5 mM 0.41 mL 2.03 mL 4.06 mL
10 mM 0.2 mL 1.02 mL 2.03 mL
50 mM 0.04 mL 0.2 mL 0.41 mL

Molarity Calculator

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Product Datasheets for Muramyl Dipeptide

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References for Muramyl Dipeptide

References are publications that support the biological activity of the product.

Lessard et al (2017) Triggering of NOD2 receptor converts inflammatory Ly6Chigh into Ly6Clow monocytes with patrolling properties. Cell Rep. 20 1830 PMID: 28834747

If you know of a relevant reference for Muramyl Dipeptide, please let us know.

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Keywords: Muramyl Dipeptide, Muramyl Dipeptide supplier, NOD2, nod-like, receptors, activates, activators, bacterial, peptidoglycan, innate, immunity, pattern, recognition, Inflammasomes, 6366, Tocris Bioscience

Citations for Muramyl Dipeptide

Citations are publications that use Tocris products.

Currently there are no citations for Muramyl Dipeptide. Do you know of a great paper that uses Muramyl Dipeptide from Tocris? Please let us know.

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Literature in this Area

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