MS049 oxalate salt

Pricing Availability Delivery Time Qty
Cat.No. 5685 - MS049 oxalate salt | C15H24N2O.C2H2O4
Description: Potent and selective PRMT4 and PRMT6 inhibitor
Chemical Name: N-Methyl-4-(phenylmethoxy)-1-piperidineethanamine oxalate salt
Purity: ≥98% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Potent and selective PRMT4 and PRMT6 inhibitor.

Licensing Information

This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the MS049 probe summary on the SGC website.

Technical Data

M. Wt 338.4
Formula C15H24N2O.C2H2O4
Storage Desiccate at RT
Purity ≥98% (HPLC)
PubChem ID 121513883
InChI Key RWKUVRQLFRJTTR-UHFFFAOYSA-N
Smiles CNCCN(CC2)CCC2OCC1=CC=CC=C1.OC(C(O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 6.77 20
water 33.84 100

Preparing Stock Solutions

The following data is based on the product molecular weight 338.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.96 mL 14.78 mL 29.55 mL
5 mM 0.59 mL 2.96 mL 5.91 mL
10 mM 0.3 mL 1.48 mL 2.96 mL
50 mM 0.06 mL 0.3 mL 0.59 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Shen et al (2016) Discovery of a potent, selective, and cell-active dual inhibitor of protein arginine methyltransferase 4 and protein arginine methyltransferase 6. J.Med.Chem. 59 9124 PMID: 27584694


If you know of a relevant reference for MS049 oxalate salt, please let us know.

View Related Products by Product Action

View all Protein Arginine Methyltransferase Inhibitors

Keywords: PRMT4 PRMT6 protein arginine methyltransferases inhibits inhibitors 1502816-23-0 Protein Arginine Methyltransferases

Citations for MS049 oxalate salt

Citations are publications that use Tocris products.

Currently there are no citations for MS049 oxalate salt. Do you know of a great paper that uses MS049 oxalate salt from Tocris? If so please let us know.

Commented out for usability testing

Reviews

TODO: Add Reviews

Literature in this Area

Cancer

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis
Epigenetics

Epigenetics Scientific Review

Written by Susanne Müller-Knapp and Peter J. Brown, this review gives an overview of the development of chemical probes for epigenetic targets, as well as the impact of these tool compounds being made available to the scientific community. In addition, their biological effects are also discussed. Epigenetic compounds available from Tocris are listed.

Epigenetics

Epigenetics Research Bulletin

Produced by Tocris and updated in 2014, the epigenetics research bulletin gives an introduction into mechanisms of epigenetic regulation, and highlights key Tocris products for epigenetics targets including:

  • Bromodomains
  • DNA Methyltransferases
  • Histone Deacetylases
  • Histone Demethylases
  • Histone Methyltransferases

Pathways for MS049 oxalate salt

Protocols

TODO: Add Protocols