L-655,240

Discontinued Product

L-655,240 (Cat. No. 1698) has been withdrawn from sale for commercial reasons.
Description: Potent, selective thromboxane A2/prostaglandin endoperoxide antagonist
Chemical Name: 1-[(4-Chlorophenyl)methyl]-5-fluoro-α,α,3-trimethyl-1H-indole-2-propanoic acid
Purity: ≥99% (HPLC)
Datasheet
Citations (1)
Reviews
Literature (5)

Biological Activity for L-655,240

Potent and selective thromboxane A2/prostaglandin endoperoxide receptor antagonist. pA2 values are 8 - 8.4 in guinea pig smooth muscle; IC50 = 7 nM for inhibition of human platelet aggregation. Orally active in vivo.

Technical Data for L-655,240

M. Wt 373.85
Formula C21H21ClFNO2
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 103253-15-2
PubChem ID 122070
InChI Key JLPYLHLUHJOPNL-UHFFFAOYSA-N
Smiles CC1=C(CC(C)(C)C(O)=O)N(CC2=CC=C(Cl)C=C2)C2=CC=C(F)C=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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Keywords: L-655,240, L-655,240 supplier, Potent, selective, thromboxane, A2, endoperoxide, TP, antagonists, Prostanoid, prostaglandins, prostacyclins, eicosanoids, L655240, Receptors, 1698, Tocris Bioscience

1 Citation for L-655,240

Citations are publications that use Tocris products. Selected citations for L-655,240 include:

Wong et al (2009) Cyclooxygenase-2-derived prostaglandin F2alpha mediates endothelium-dependent contractions in the aortae of hamsters with increased impact during aging. Circ Res 104 228 PMID: 19096033


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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

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