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Muscarinic antagonist, bronchodilator. N-Isopropyl salt of atropine.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 412.37. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||4.85 mL||24.25 mL||48.5 mL|
|2.5 mM||0.97 mL||4.85 mL||9.7 mL|
|5 mM||0.49 mL||2.43 mL||4.85 mL|
|25 mM||0.1 mL||0.49 mL||0.97 mL|
References are publications that support the biological activity of the product.
Fryer and Maclagan (1987) Ipratropium bromide potentiates bronchoconstriction induced by vagal nerve stimulation in the guinea-pig. Eur.J.Pharmacol. 139 187 PMID: 2958300
Merck Index 12 5089
If you know of a relevant reference for Ipratropium bromide, please let us know.
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Keywords: Ipratropium bromide, Ipratropium bromide supplier, Muscarinic, antagonists, Receptors, Acetylcholine, bronchodilator, ACh, Non-selective, Muscarinics, 0692, Tocris Bioscience
3 Citations for Ipratropium bromide
Citations are publications that use Tocris products. Selected citations for Ipratropium bromide include:
Deng et al (2013) Label-free cell phenotypic assessment of the biased agonism and efficacy of agonists at the endogenous muscarinic M3 receptors. J Pharmacol Toxicol Methods 68 323 PMID: 23933114
Woo et al (2007) Neuregulin-1 enhances depolarization-induced GABA release. Neuron 54 599 PMID: 17521572
Valeria et al (2016) A subnanomolar concentration of Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) pre-synaptically modulates glutamatergic transmission in the rat hippocampus acting through acetylcholine Neuroscience 340 551 PMID: 27816700
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Alzheimer's disease (AD) is a degenerative brain disease and the most common cause of dementia, affecting approximately 47 million people worldwide. Updated in 2015, this poster summarizes the structural and functional changes observed in the progression of this neurodegenerative disease, as well as classic AD drug targets.
Learning & Memory Poster
Recognition memory enables us to make judgements about whether or not we have encountered a particular stimulus before. This poster outlines the cellular mechanisms underlying recognition memory and its links to long-term depression, as well as the use of pharmacological intervention to assess the role of neurotransmitters in recognition memory.
Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.