Potent thromboxane receptor antagonist.
Sold with the permission of AstraZeneca UK Ltd.
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble in DMSO|
Preparing Stock Solutions
The following data is based on the product molecular weight 374.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.67 mL||13.36 mL||26.71 mL|
|5 mM||0.53 mL||2.67 mL||5.34 mL|
|10 mM||0.27 mL||1.34 mL||2.67 mL|
|50 mM||0.05 mL||0.27 mL||0.53 mL|
References are publications that support the products' biological activity.
Birch et al (1988) Studies in the guinea-pig with ICI 185,282: a thromboxane A2 receptor antagonist. J.Pharm.Pharmacol. 40 706 PMID: 2907537
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Keywords: ICI 185,282, supplier, Potent, thromboxane, A2, TXA2, receptors, antagonists, TP, Prostanoid, prostaglandins, prostacyclins, eicosanoids, ICI185282, AstraZeneca, Prostanoid, Receptors, Prostanoid, Receptors, Tocris Bioscience
1 Citation for ICI 185,282
Citations are publications that use Tocris products. Selected citations for ICI 185,282 include:
Kleinbongard et al (2011) Vasoconstrictor potential of coronary aspirate from patients undergoing stenting of saphenous vein aortocoronary bypass grafts and its pharmacological attenuation. Circ Res 108 344 PMID: 21183739
Do you know of a great paper that uses ICI 185,282 from Tocris? If so please let us know.
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