ICI 185,282

Discontinued Product

ICI 185,282 (Cat. No. 0836) has been withdrawn from sale for commercial reasons.
Description: Potent thromboxane receptor antagonist
Chemical Name: 5-(Z)-7-(4-o-Hydroxyphenyl-2-trifluoromethyl-1,3 dioxan-cis-5-yl)heptenoic acid
Citations (1)

Biological Activity for ICI 185,282

Potent thromboxane receptor antagonist.

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Technical Data for ICI 185,282

M. Wt 374.36
Formula C18H21F3O5
Storage Desiccate at -20°C
CAS Number 106393-80-0
PubChem ID 5311390
Smiles OC(=O)CCC\C=C/C[C@@H]1CO[C@@H](O[C@@H]1C1=C(O)C=CC=C1)C(F)(F)F

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for ICI 185,282

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service

References for ICI 185,282

References are publications that support the biological activity of the product.

Birch et al (1988) Studies in the guinea-pig with ICI 185,282: a thromboxane A2 receptor antagonist. J.Pharm.Pharmacol. 40 706 PMID: 2907537

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Keywords: ICI 185,282, ICI 185,282 supplier, Potent, thromboxane, A2, TXA2, receptors, antagonists, TP, Prostanoid, prostaglandins, prostacyclins, eicosanoids, ICI185282, AstraZeneca, Receptors, 0836, Tocris Bioscience

1 Citation for ICI 185,282

Citations are publications that use Tocris products. Selected citations for ICI 185,282 include:

Kleinbongard et al (2011) Vasoconstrictor potential of coronary aspirate from patients undergoing stenting of saphenous vein aortocoronary bypass grafts and its pharmacological attenuation. Circ Res 108 344 PMID: 21183739

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