NMDA and metabotropic glutamate receptor agonist.
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 158.11. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||6.32 mL||31.62 mL||63.25 mL|
|5 mM||1.26 mL||6.32 mL||12.65 mL|
|10 mM||0.63 mL||3.16 mL||6.32 mL|
|50 mM||0.13 mL||0.63 mL||1.26 mL|
References are publications that support the products' biological activity.
Johnston et al (1968) Central actions of ibotenic acid and muscimol. Biochem.Pharmacol. 17 2488 PMID: 5752907
Nakanishi (1992) Molecular diversity of glutamate receptors and implications for brain functions. Science 258 597 PMID: 1329206
Pin and Duvoisin (1995) The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34 1 PMID: 7623957
Watkins and Evans (1981) Excitatory amino acid transmitters. Annu.Rev.Pharmacol.Toxicol. 21 165 PMID: 6112965
If you know of a relevant reference for Ibotenic acid, please let us know.
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Keywords: Ibotenic acid, supplier, Non-Selective, NMDA, agonists, mGlur, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, Metabotropic, NMDA, Receptors, Non-selective, mGlu, NMDA, Receptors, Tocris Bioscience
3 Citations for Ibotenic acid
Citations are publications that use Tocris products. Selected citations for Ibotenic acid include:
Karlsson et al (2013) Exaggerated cue-induced reinstatement of cocaine seeking but not incubation of cocaine craving in a developmental rat model of schizophrenia. Psychopharmacology (Berl) 226 45 PMID: 23010798
Pitts and Takahashi (2011) The central amygdala nucleus via corticotropin-releasing factor is necessary for time-limited consolidation processing but not storage of contextual fear memory. Neuroreport 95 86 PMID: 21093597
Renouard et al (2015) The supramammillary nucleus and the claustrum activate the cortex during REM sleep. Neurobiol Learn Mem 1 e1400177 PMID: 26601158
Do you know of a great paper that uses Ibotenic acid from Tocris? If so please let us know.
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